Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 9/20 | 0.45 |
| ▸ | CNR2 | P34972 | 7/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997864 | 0.88 | TOP1 (0.43) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL1430267 | 0.87 | TOP1 (0.43) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3004410 | 0.86 | FEN1 (0.41) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL28787968 | 0.86 | FEN1 (0.41) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL13008010 | 0.86 | CNR1 (0.46) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3006912 | 0.86 | CNR1 (0.46) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL13008011 | 0.86 | CNR1 (0.46) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3000696 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL4149885 | 0.84 | LMNA (0.56) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL3003439 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170791-A1 | MACROLONES | GLAXO SMITH KLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O A CORPORATION | 2009-07-02 | — | — | US | disclosed |
| US-20090170791-A1 | MACROLONES | GLAXO SMITH KLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O A CORPORATION | 2009-07-02 | — | — | US | disclosed |
| US-20090170791-A1 | MACROLONES | GLAXO SMITH KLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O A CORPORATION | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170791-A1 | MACROLONES | CYP51A1, MRPL21, LSS | KDM4E 4180/4885ALDH1A1 3645/4885HPGD 2439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.