SCHEMBL4143753

SCHEMBL4143753

Clc1ccccc1P(c1ccccc1)c1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl.[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].[Au].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
DRD1 P21728 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29996019 0.84 CYP3A4 (0.50) CYP3A4TDP1ESR1ESR2LMNA
SCHEMBL2996679 0.82 CYP3A4 (0.55) CYP3A4TDP1ESR1ESR2LMNA
SCHEMBL30046611 0.82 CYP3A4 (0.52) CYP3A4TDP1ESR1ESR2LMNA
SCHEMBL9854456 0.82 CYP3A4 (0.52) CYP3A4TDP1ESR1ESR2LMNA
SCHEMBL2454266 0.82 CYP3A4 (0.52) CYP3A4TDP1ESR1ESR2LMNA
SCHEMBL29518446 0.82 CYP3A4 (0.52) CYP3A4TDP1ESR1ESR2LMNA
SCHEMBL31158056 0.80 CYP3A4 (0.50) CYP3A4TDP1ESR1ESR2LMNA
SCHEMBL29672644 0.80 CYP3A4 (0.50) CYP3A4TDP1ESR1ESR2LMNA
SCHEMBL31258429 0.78 CYP3A4 (0.48) CYP3A4TDP1ESR1ESR2LMNA
SCHEMBL10596637 0.78 CYP3A4 (0.48) CYP3A4TDP1ESR1ESR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7626192-B2 Forming arrays of metal, alloy, semiconductor or magnetic nanoparticles is described; embodiment of the method comprises placing a scaffold on a substrate, the scaffold comprising, for example, polynucleotides and/or polypeptides, and coupling nanoparticles to scaffold State of Oregon Acting by the Through the State Board of Higher Education on Behalf of the University of Oregon (US) 2009-12-01 US disclosed
US-20090155573-A1 SCAFFOLD-ORGANIZED METAL, ALLOY, SEMICONDUCTOR AND/OR MAGNETIC CLUSTERS AND ELECTRONIC DEVICES MADE USING SUCH CLUSTERS State of Oregon acting by and through the State Board of Higher Education on behalf of the 2009-06-18 US disclosed
US-20090047753-A1 Scaffold-organized clusters and electronic devices made using such clusters The State of Oregon acting by and through the State Board of Higher Education on behalf of the 2009-02-19 US disclosed
US-7442573-B2 Scaffold-organized clusters and electronic devices made using such clusters STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 2008-10-28 US disclosed
US-7326954-B2 Scaffold-organized metal, alloy, semiconductor and/or magnetic clusters and electronic devices made using such clusters STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 2008-02-05 US disclosed
US-20060081835-A1 Scaffold-organized clusters and electronic devices made using such clusters STATE OF OR ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDU. ON BEHALF OF THE UNIVERSITY OF OREGON 2006-04-20 US disclosed
US-20060063299-A1 Scaffold-organized clusters and electronic devices made using such clusters STATE OF OREGON ACTING BY & THROUGH THE STATE BOARD OF HIGHER EDUC. ON BEHALF OF THE UNIV. OF OR 2006-03-23 US disclosed
US-6872971-B2 Scaffold-organized clusters and electronic made using such clusters THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 2005-03-29 US disclosed
US-20040203074-A1 Scaffold-organized metal, alloy, semiconductor and/or magnetic clusters and electronic devices made using such clusters NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA 2004-10-14 US disclosed
US-20040166673-A1 Scaffold-organized clusters and electronic devices made using such clusters THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF 2004-08-26 US disclosed
US-6730537-B2 COUPLING ARRAYS OF METAL, ALLOY, SEMICONDUCTOR OR MAGNETIC CLUSTERS SCAFFOLD COMPRISING, FOR EXAMPLE, POLYNUCLEOTIDES AND/OR POLYPEPTIDES THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON 2004-05-04 US disclosed
WO-2004002508-A1 PARTICLES BY FACILE LIGAND EXCHANGE REACTIONS THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 2004-01-08 WO disclosed
US-20030077625-A1 Nanoparticle solid support for detecting preferential particles in sample STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALFOF THE UNIVERSITY OF OREGON 2003-04-24 US disclosed
US-20020146742-A1 Scaffold-organized metal, alloy, semiconductor and/or magnetic clusters and electronic devices made using such clusters NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA 2002-10-10 US disclosed
US-20020016306-A1 Scaffold-organized clusters and electronic devices made using such clusters NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA 2002-02-07 US disclosed
WO-2001073150-A1 SCAFFOLD-ORGANIZED CLUSTERS AND ELECTRONIC DEVICES MADE USING SUCH CLUSTERS THE STATE OF OREGON, ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 2001-10-04 WO disclosed
WO-1998053841-A1 SCAFFOLD-ORGANIZED METAL, ALLOY, SEMICONDUCTOR AND/OR MAGNETIC CLUSTERS AND ELECTRONIC DEVICES MADE USING SUCH CLUSTERS THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF OREGON (US) 1998-12-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016306-A1 Scaffold-organized clusters and electronic devices made using such clusters ILK, ECPAS, GAP43 CYP3A4 4823/4885TDP1 1614/4885ESR1 3671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.