Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12056990 | 0.81 | — | — | |
| SCHEMBL414328 | 0.74 | SLC6A3 (0.34) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL415454 | 0.72 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4KCNH2ALDH1A1 | |
| SCHEMBL415423 | 0.65 | CYP2D6 (0.30) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL17707506 | 0.65 | TACR2 (0.32) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL17707509 | 0.65 | TACR2 (0.32) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL17707507 | 0.65 | TACR2 (0.32) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL444129 | 0.64 | KCNQ2 (0.36) | SLC6A3SLC6A2SLC6A4KCNH2ALDH1A1 | |
| SCHEMBL444534 | 0.63 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL413930 | 0.62 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065225-A1 | HETEROARYL PYRROLIDINYL AND PIPERIDINYL KETONE DERIVATIVES AND USES THEREOF | IYER PRAVIN (US) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065225-A1 | HETEROARYL PYRROLIDINYL AND PIPERIDINYL KETONE DERIVATIVES AND USES THEREOF | CNKSR1, RB1, AR | SLC6A3 4745/4885SLC6A2 4870/4885SLC6A4 4855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.