Nitrapyrin

Nitrapyrin

SCHEMBL41442

Clc1cccc(C(Cl)(Cl)Cl)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 1.00
TSHR P16473 1/20 1.00
NFE2L2 Q16236 5/20 0.39
GAA P10253 2/20 0.38
ALDH1A1 P00352 4/20 0.37
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
AGTR1 P30556 1/20 0.35
SLC40A1 Q9NP59 1/20 0.35
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
HTR3E A5X5Y0 2/20 0.34
HTR3B O95264 2/20 0.34
HTR3A P46098 2/20 0.34
HTR3D Q70Z44 2/20 0.34
HTR3C Q8WXA8 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrapyrin SCHEMBL4115039 1.00 CYP3A4 (1.00) CYP3A4TSHRNFE2L2GAAALDH1A1
Nitrapyrin SCHEMBL29349488 1.00 CYP3A4 (1.00) CYP3A4TSHRNFE2L2GAAALDH1A1
Nitrapyrin SCHEMBL21758631 0.98 CYP3A4 (0.95) CYP3A4TSHRNFE2L2GAAALDH1A1
Nitrapyrin SCHEMBL9644890 0.88 CYP3A4 (0.77) CYP3A4TSHRNFE2L2GAAALDH1A1
Nitrapyrin SCHEMBL18065800 0.88 TSHR (0.77) CYP3A4TSHRNFE2L2GAAALDH1A1
Nitrapyrin SCHEMBL30415064 0.84 TSHR (0.71) CYP3A4TSHRNFE2L2GAAALDH1A1
SCHEMBL3297356 0.84 TSHR (0.71) CYP3A4TSHRALDH1A1PGK1PGK2
SCHEMBL17141418 0.81 CYP3A4 (0.68) CYP3A4TSHRNFE2L2ALDH1A1PGK1
SCHEMBL17141411 0.81 CYP3A4 (0.68) CYP3A4TSHRNFE2L2ALDH1A1PGK1
SCHEMBL11391263 0.79 CYP3A4 (0.64) CYP3A4TSHRNFE2L2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13299 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747215-A1 PYRAZOLE DERIVATIVES AS DUAL FUNCTION UREASE AND NITRIFICATION INHIBITOR Sabic Agri-Nutrients Company (SA) 2026-05-27 EP claimed
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
WO-2026099762-A1 AMINODITHIOCARBAMATE DERIVATIVES AS DUAL FUNCTION UREASE AND NITRIFICATION INHIBITOR SABIC Agri-Nutrients Company (SA) 2026-05-15 WO claimed
US-12623979-B2 Nitrification inhibitors to improve fertilizer efficiency SOILGENIC TECHNOLOGIES, LLC (US) 2026-05-12 US claimed
US-12582116-B2 Agricultural formulations DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-24 US claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-20260068884-A1 COMPOSITION USED FOR KILLING FUNGI AND METHOD FOR APPLYING COMPOSITION JIANGSU FLAG CHEMICAL INDUSTRY CO., LTD. (CN) 2026-03-12 US claimed
EP-4682136-A2 INHIBITORS OF SOIL NITRIFICATION AND PROCESSES TO PREVENT SAME Tessenderlo Group NV (BE) 2026-01-21 EP claimed
EP-3294058-B1 AGROCHEMICAL EMULSIONS CRODA INC (US) 2025-12-24 EP claimed
US-12497341-B2 Reaction methods for producing nitrogenous phosphoryl compounds that are in situ fluid compositions SOILGENIC TECHNOLOGIES, LLC (US) 2025-12-16 US claimed
US-4487935-A GOOD MIXING, MULTISTAGE KALAMA CHEMICAL, INC. (US) 1984-12-11 US claimed
US-4474789-A (Trichloromethyl)pyridine compounds useful for promoting growth and/or improving feed utilization efficiency in ruminants THE DOW CHEMICAL COMPANY (US) 1984-10-02 US claimed
EP-0030101-B1 PREPARATION OF (DICHLOROMETHYL) PYRIDINES BY REDUCTIVE DECHLORINATION THE DOW CHEMICAL COMPANY (US) 1983-06-08 EP claimed
US-4327220-A Process for reducing picoline derivatives using copper catalyst THE DOW CHEMICAL COMPANY (US) 1982-04-27 US claimed
EP-0030101-A1 Preparation of (dichloromethyl) pyridines by reductive dechlorination THE DOW CHEMICAL COMPANY (US) 1981-06-10 EP claimed
US-4266964-A SAID ANTIDOTES BEING CHLOROPYRIDINE COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1981-05-12 US claimed
US-4260766-A Preparation of (dichloromethyl) pyridines by reductive dechlorination THE DOW CHEMICAL COMPANY (US) 1981-04-07 US claimed
US-4256894-A REACTING LIQUID CHLORO-SUBSTITUTED (TRICHLOROMETHYL) PYRIDINE WITH CHLORINE IN THE PRESENCE OF A LEWIS ACID CATALYST THE DOW CHEMICAL COMPANY (US) 1981-03-17 US claimed
EP-0006348-A1 Surfactant compositions and biologically active formulations prepared therewith ICI AMERICAS INC. (US) 1980-01-09 EP claimed
EP-0005064-A1 Process for preparing 2,3,5,6-tetrachloropyridine THE DOW CHEMICAL COMPANY (US) 1979-10-31 EP claimed