Nitrapyrin

Nitrapyrin

SCHEMBL29349488

Clc1cccc(C(Cl)(Cl)Cl)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 1.00
TSHR P16473 1/20 1.00
NFE2L2 Q16236 5/20 0.39
GAA P10253 2/20 0.38
ALDH1A1 P00352 4/20 0.37
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
AGTR1 P30556 1/20 0.35
SLC40A1 Q9NP59 1/20 0.35
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
HTR3E A5X5Y0 2/20 0.34
HTR3B O95264 2/20 0.34
HTR3A P46098 2/20 0.34
HTR3D Q70Z44 2/20 0.34
HTR3C Q8WXA8 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrapyrin SCHEMBL4115039 1.00 CYP3A4 (1.00) CYP3A4TSHRNFE2L2GAAALDH1A1
Nitrapyrin SCHEMBL41442 1.00 CYP3A4 (1.00) CYP3A4TSHRNFE2L2GAAALDH1A1
Nitrapyrin SCHEMBL21758631 0.98 CYP3A4 (0.95) CYP3A4TSHRNFE2L2GAAALDH1A1
Nitrapyrin SCHEMBL9644890 0.88 CYP3A4 (0.77) CYP3A4TSHRNFE2L2GAAALDH1A1
Nitrapyrin SCHEMBL18065800 0.88 TSHR (0.77) CYP3A4TSHRNFE2L2GAAALDH1A1
Nitrapyrin SCHEMBL30415064 0.84 TSHR (0.71) CYP3A4TSHRNFE2L2GAAALDH1A1
SCHEMBL3297356 0.84 TSHR (0.71) CYP3A4TSHRALDH1A1PGK1PGK2
SCHEMBL17141418 0.81 CYP3A4 (0.68) CYP3A4TSHRNFE2L2ALDH1A1PGK1
SCHEMBL17141411 0.81 CYP3A4 (0.68) CYP3A4TSHRNFE2L2ALDH1A1PGK1
SCHEMBL11391263 0.79 CYP3A4 (0.64) CYP3A4TSHRNFE2L2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1480 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
CN-121044944-B Preparation method of intelligent controlled-release microcapsule of nitrification inhibitor 吉林农业大学 2026-02-27 CN claimed
US-20250326839-A1 TREATMENT OF DISEASES RELATED TO COLONY-STIMULATING FACTOR 1 RECEPTOR DYSFUNCTION USING TREM2 AGONISTS VIGIL NEUROSCIENCE INC (US) 2025-10-23 US claimed
US-20250326723-A1 Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly UNIV NORTHWESTERN (US) 2025-10-23 US claimed
US-20250313531-A1 Formulated and/or Co-Formulated Liposome Compositions Containing IDO Antagonist Prodrugs Useful in the Treatment of Cancer and Methods Thereof NAMMI THERAPEUTICS, INC. 2025-10-09 US claimed
US-20250282866-A1 TREATMENT OF DISEASES RELATED TO ATP-BINDING CASSETTE TRANSPORTER 1 DYSFUNCTION USING TREM2 AGONISTS VIGIL NEUROSCIENCE INC (US) 2025-09-11 US claimed
EP-4590349-A1 SOLID AND COMPACT BIOMATERIAL, METHOD FOR ITS PREPARATION AND KIT FOR FILLING BONE CAVITIES TECRES S.P.A. (IT) 2025-07-30 EP claimed
US-20250236572-A1 METHOD FOR SEPARATING METHANE USING HYDRATE GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2025-07-24 US claimed
EP-4581150-A1 PREPARATION AND USE OF BLOCKED SUBSTRATES Illumina, Inc. (US) 2025-07-09 EP claimed
WO-2025101765-A9 NOVEL LIVER-TARGETING GLUCOCORTICOID PRODRUGS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2025-06-19 WO claimed
CN-110602948-B Microencapsulated nitrification inhibitor compositions 美国陶氏益农公司 2022-04-01 CN claimed
WO-2022053659-A2 HETEROCYCLIC COMPOUNDS USED AS NITRIFICATION INHIBITOR EUROCHEM ANTWERPEN (BE) 2022-03-17 WO claimed
WO-2022053660-A2 N-HETEROCYCLIC COMPOUNDS USED AS NITRIFICATION INHIBITOR EUROCHEM ANTWERPEN (BE) 2022-03-17 WO claimed
WO-2022053661-A2 PYRAZOLO[3,4-B]PYRIDINE-4-CARBOXAMIDE NITRIFICATION INHIBITOR EUROCHEM ANTWERPEN (BE) 2022-03-17 WO claimed
CN-114163275-A Soil conditioner with balanced microorganisms and preparation method thereof 中国科学院沈阳应用生态研究所 2022-03-11 CN claimed
CN-109415278-B Compositions suitable for use in the preparation of fertilizers, methods of preparing these compositions, and methods of preparing fertilizers using the compositions 美利肯公司 2022-02-22 CN claimed
WO-2022031843-A1 METHODS OF CONTROLLING THE RIPENING OF AGRICULTURAL PRODUCTS APEEL TECHNOLOGY, INC. (US) 2022-02-10 WO claimed
WO-2022032293-A2 TREATMENT OF DISEASES RELATED TO COLONY-STIMULATING FACTOR 1 RECEPTOR DYSFUNCTION USING TREM2 AGONISTS VIGIL NEUROSCIENCE, INC. (US) 2022-02-10 WO claimed
US-20220039416-A1 METHODS OF CONTROLLING THE RIPENING OF AGRICULTURAL PRODUCTS APEEL TECHNOLOGY, INC. 2022-02-10 US claimed
CN-113999070-A Alkaline soil conditioner and preparation method thereof 中国科学院沈阳应用生态研究所 2022-02-01 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313531-A1 Formulated and/or Co-Formulated Liposome Compositions Containing IDO Antagonist Prodrugs Useful in the Treatment of Cancer and Methods Thereof IDO1, IDO2, KYNU CYP3A4 2038/4885TSHR 4033/4885NFE2L2 3357/4885
US-20250326723-A1 Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly CRABP2, RARB, RARA CYP3A4 2954/4885TSHR 631/4885NFE2L2 1885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.