SCHEMBL4145111

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4144387	0.92	AR (0.47)	ARPGRSMN1; SMN2ALDH1A1MAPT
	SCHEMBL4150461	0.91	AR (0.43)	ARPGRSMN1; SMN2HPGDNPC1
	SCHEMBL4150955	0.91	AR (0.43)	ARPGR
	SCHEMBL13777385	0.90	AR (0.42)	ARPGRNPC1RAB9A
	SCHEMBL4151282	0.90	AR (0.46)	ARPGRSMN1; SMN2ALDH1A1MAPT
	SCHEMBL4153133	0.89	AR (0.52)	ARPGRSMN1; SMN2ALDH1A1LMNA
	SCHEMBL4150525	0.89	AR (0.43)	ARPGRSMN1; SMN2ALDH1A1MAPT
	SCHEMBL4137709	0.89	AR (0.52)	ARPGRALDH1A1MAPTKDM4E
	SCHEMBL4140528	0.89	AR (0.43)	ARPGRSMN1; SMN2ALDH1A1MAPT
	SCHEMBL13777367	0.88	AR (0.43)	ARPGRSMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.