Phthalic Acid

Phthalic Acid

SCHEMBL414513

CC12C=CC(CC1)C2.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
ALDH1A1 P00352 4/20 0.42
ALOX15 P16050 2/20 0.42
AKR1C3 P42330 2/20 0.36
GAA P10253 2/20 0.36
TRPA1 O75762 1/20 0.36
KDM4E B2RXH2 3/20 0.35
P2RX7 Q99572 1/20 0.35
MYC P01106 2/20 0.35
NR4A1 P22736 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CPB1 P15086 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
HMGB1 P09429 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1416852 0.70
Phthalic Acid SCHEMBL22471697 0.67 ALDH1A1 (0.64) ALDH1A1ALOX15AKR1C3GAAKDM4E
Phthalic Acid SCHEMBL11171682 0.66 ALDH1A1 (0.56) TDP1CYP3A4CYP2D6CYP2C9CYP2C19
Phthalic Acid SCHEMBL23275565 0.65 ALDH1A1 (0.61) ALDH1A1ALOX15AKR1C3GAAKDM4E
Phthalic Acid SCHEMBL27470430 0.65 ALDH1A1 (0.88) TDP1CYP3A4CYP2C9ALDH1A1ALOX15
Phthalic Acid SCHEMBL4396104 0.65 ALDH1A1 (0.88) TDP1CYP3A4CYP2C9ALDH1A1ALOX15
Phthalic Acid SCHEMBL30575217 0.65 ALDH1A1 (0.88) TDP1CYP3A4CYP2C9ALDH1A1ALOX15
Phthalic Acid SCHEMBL4797005 0.65 ALDH1A1 (0.88) TDP1CYP3A4CYP2C9ALDH1A1ALOX15
Phthalic Acid SCHEMBL10477086 0.65 ALDH1A1 (1.00) ALDH1A1ALOX15AKR1C3KDM4EMYC
Phthalic Acid SCHEMBL5668586 0.65 ALDH1A1 (1.00) ALDH1A1ALOX15AKR1C3KDM4EMYC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8779032-B2 Epoxy resin based core filler material developing low exothermic heat 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-07-15 US disclosed
EP-2414425-B1 EPOXY RESIN BASED CORE FILLER MATERIAL DEVELOPING LOW EXOTHERMIC HEAT 3M INNOVATIVE PROPERTIES CO (US) 2014-04-23 EP disclosed
US-20120022185-A1 EPOXY RESIN BASED CORE FILLER MATERIAL DEVELOPING LOW EXOTHERMIC HEAT 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-01-26 US disclosed
CN-1083871-C Epoxy Adhesives Containing Dithiooxamide Adhesion Promoters MINNESOTA MINING & MFG (US) 2002-05-01 CN disclosed
CN-1180369-A Epoxy adhesives containing dithio * amide adhesion promoters MINNESOTA MINNG AND MANUFACTUR (US) 1998-04-29 CN disclosed