⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145379 | 1.00 | — | — | |
| Trifluoroacetic Acid SCHEMBL4143531 | 0.94 | PRKCA (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL4143526 | 0.94 | PRKCA (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL4153237 | 0.79 | PRKCA (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL4153234 | 0.79 | PRKCA (0.39) | — | |
| SCHEMBL2156818 | 0.73 | PRKCA (0.32) | — | |
| SCHEMBL4145900 | 0.73 | PRKCA (0.40) | — | |
| SCHEMBL4152405 | 0.73 | PRKCA (0.40) | — | |
| SCHEMBL4152401 | 0.73 | PRKCA (0.40) | — | |
| SCHEMBL4140597 | 0.73 | PRKCA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-05-28 | — | — | US | disclosed |