SCHEMBL4145665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26704779	0.81	SMN1; SMN2 (0.55)	SLC6A2SLC6A4SLC6A3MEN1KMT2A
	SCHEMBL4150070	0.79	IGFBP3 (0.40)	ROCK2RPS6KA3CYP19A1GAA
	SCHEMBL600527	0.73	UGT2B7 (0.68)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL30033673	0.73	UGT2B7 (0.68)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL23882840	0.72	CYP19A1 (0.45)	CYP3A4CYP19A1CYP11B1CYP11B2
	SCHEMBL4137944	0.72	UGT2B7 (0.45)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL10034523	0.72	RPS6KA3 (0.38)	CYP3A4RPS6KA3CYP17A1CYP19A1CYP11B1
	SCHEMBL26326655	0.71	UGT2B7 (0.55)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL4085392	0.69	CYP3A4 (0.42)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL17237857	0.68	UGT2B7 (0.52)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.