SCHEMBL4145872

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4145878	1.00	KDR (0.45)	KDRFGFR1NTRK1NTRK2LCK
	SCHEMBL4145333	0.90	KDR (0.46)	KDRFGFR1NTRK1NTRK2LCK
	SCHEMBL4145329	0.90	KDR (0.46)	KDRFGFR1NTRK1NTRK2LCK
	SCHEMBL4145304	0.87	RAB9A (0.34)	KDRFGFR1NTRK1NTRK2LCK
	SCHEMBL4145309	0.87	RAB9A (0.34)	KDRFGFR1NTRK1NTRK2LCK
	SCHEMBL4145366	0.86	KDR (0.44)	KDRFGFR1LCKAURKAAURKB
	SCHEMBL4145369	0.86	KDR (0.44)	KDRFGFR1LCKAURKAAURKB
	SCHEMBL4145370	0.85	PIM1 (0.36)	KDRFGFR1TYK2
	SCHEMBL4145364	0.85	PIM1 (0.36)	KDRFGFR1TYK2
	SCHEMBL4153068	0.84	KDR (0.56)	KDRFGFR1NTRK1NTRK2LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.