⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868986 | 0.78 | — | — | |
| SCHEMBL7202635 | 0.78 | — | — | |
| SCHEMBL4311579 | 0.72 | CYP2C9 (0.33) | — | |
| SCHEMBL25729168 | 0.69 | — | — | |
| SCHEMBL11426676 | 0.69 | — | — | |
| SCHEMBL12221453 | 0.69 | — | — | |
| SCHEMBL6051450 | 0.69 | — | — | |
| SCHEMBL6051456 | 0.69 | — | — | |
| SCHEMBL14220785 | 0.66 | — | — | |
| SCHEMBL510520 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7037931-B2 | Corticotropin releasing factor moderator; analgesics; drug abruse, drug dependency; schizophrenia | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-02 | — | — | US | claimed |
| JP-2006501194-A | — | — | 2006-01-12 | — | — | JP | claimed |
| EP-1525190-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004007463-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-01-22 | — | — | WO | claimed |
| CN-1022036-C | Process for preparing cephalosporim compounds | KAKEN PHARMA CO LTD (JP) | 1993-09-08 | — | — | CN | claimed |
| EP-0137534-B1 | ONE-POT PROCESS FOR PREPARATION OF 7BETA-AMINO- AND 7BETA-ACYLAMINO- 3-SUBSTITUTED METHYL-3-CEPHEM-4-CARBOXYLIC ACID DERIVATIVES AND PROCESS FOR DEOXYGENATION OF 7BETA-ACYLAMINO-3-CEPHEM-4-CARBOXYLIC ACID 1-OXIDE DERIVATIVES | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | claimed |
| EP-0068403-B1 | CEPHALOSPORIN COMPOUND | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-08-13 | — | — | EP | claimed |
| EP-0137534-A2 | One-pot process for preparation of 7beta-amino- and 7beta-acylamino- 3-substituted methyl-3-cephem-4-carboxylic acid derivatives and process for deoxygenation of 7beta-acylamino-3-cephem-4-carboxylic acid 1-oxide derivatives | GIST-BROCADES N.V. (NL) | 1985-04-17 | — | — | EP | claimed |
| US-4200747-A | 7-2-Indolyl acetamido cephalosporin derivatives | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1980-04-29 | — | — | US | claimed |
| EP-1781617-A4 | ALPHA, BETA-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-24 | — | — | EP | disclosed |
| US-7465808-B2 | CCK-1 receptor modulators | JANSSEN PHARMACEUTICA, N.V. (BE) | 2008-12-16 | — | — | US | disclosed |
| EP-1781617-A2 | ALPHA, BETA-UNSATURATED ESTERS AND ACIDS BY STEREOSELECTIVE DEHYDRATION | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-09 | — | — | EP | disclosed |
| US-7037931-B2 | Corticotropin releasing factor moderator; analgesics; drug abruse, drug dependency; schizophrenia | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-02 | — | — | US | disclosed |
| EP-1641762-A2 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-04-05 | — | — | EP | disclosed |
| US-4154831-A | Cephalosporins having an α-acylaminoacetic acid side chain | CIBA-GEIGY CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4139703-A | ANTIBIOTICS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1979-02-13 | — | — | US | disclosed |
| US-4098888-A | THIAZOLYLACETAMIDO CEPHALOSPORIN TYPE COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-07-04 | — | — | US | disclosed |
| US-4061861-A | ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-4048161-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4041161-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |