Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 7/20 | 0.57 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.57 |
| ▸ | SSTR2 | P30874 | 6/20 | 0.57 |
| ▸ | SSTR3 | P32745 | 6/20 | 0.57 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.57 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | CDC25B | P30305 | 5/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL414620 | 0.91 | TACR1 (0.48) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL6890170 | 0.89 | SSTR4 (0.57) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL7907049 | 0.89 | SSTR4 (0.57) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL7908649 | 0.89 | SSTR4 (0.57) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL7908653 | 0.89 | SSTR4 (0.57) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL6888307 | 0.89 | SSTR4 (0.57) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL14088875 | 0.86 | SSTR1 (0.46) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL22677471 | 0.86 | TACR1 (0.46) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL14088874 | 0.86 | GJB2 (0.47) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL6229615 | 0.85 | SSTR4 (0.76) | SSTR4SSTR1SSTR2SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8974793-B2 | Methods and systems for inducing immunologic tolerance to non-self antigens | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2015-03-10 | — | — | US | disclosed |
| US-20120021056-A1 | Methods and Systems for Inducing Immunologic Tolerance to Non-Self Antigens | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021056-A1 | Methods and Systems for Inducing Immunologic Tolerance to Non-Self Antigens | CD47, CD74, HLA-C | SSTR4 1291/4885SSTR1 1386/4885SSTR2 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.