Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | MC4R | P32245 | 14/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4006667 | 0.81 | KCNH2 (0.56) | KCNH2MC4RTP53LMNAHPGD | |
| SCHEMBL14027063 | 0.79 | MC4R (0.61) | KCNH2MC4RLMNAHPGD | |
| SCHEMBL4007682 | 0.78 | KCNH2 (0.54) | KCNH2MC4RTP53LMNAHPGD | |
| SCHEMBL4146362 | 0.76 | MC4R (0.53) | KCNH2MC4RTP53LMNAHPGD | |
| SCHEMBL4008856 | 0.72 | KDM4E (0.66) | KCNH2MC4R | |
| SCHEMBL4009250 | 0.72 | MC4R (0.56) | KCNH2MC4R | |
| SCHEMBL4068102 | 0.72 | MC4R (0.56) | KCNH2MC4RLMNAHPGD | |
| SCHEMBL4541829 | 0.71 | MC4R (0.53) | KCNH2MC4R | |
| SCHEMBL14027065 | 0.71 | MC4R (0.73) | KCNH2MC4RLMNAHPGD | |
| SCHEMBL4147186 | 0.71 | MC4R (0.54) | KCNH2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080351-A1 | COMPOUNDS WITH ANTI-EMETIC EFFECT | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2009-07-02 | — | — | WO | disclosed |