Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 16/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541826 | 0.92 | MC4R (0.55) | MC4RKCNH2 | |
| SCHEMBL4146362 | 0.76 | MC4R (0.53) | MC4RKCNH2 | |
| SCHEMBL4007682 | 0.74 | KCNH2 (0.54) | MC4RKCNH2 | |
| SCHEMBL14027063 | 0.72 | MC4R (0.61) | MC4RKCNH2 | |
| SCHEMBL4146364 | 0.71 | KCNH2 (0.52) | MC4RKCNH2 | |
| SCHEMBL4006667 | 0.71 | KCNH2 (0.56) | MC4RKCNH2 | |
| SCHEMBL4006591 | 0.70 | KDM4E (0.65) | MC4RKCNH2 | |
| SCHEMBL4147186 | 0.70 | MC4R (0.54) | MC4RKCNH2 | |
| SCHEMBL4357418 | 0.69 | KCNH2 (0.56) | MC4RKCNH2 | |
| SCHEMBL4068102 | 0.69 | MC4R (0.56) | MC4RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2072050-A1 | Compounds with anti-emetic effect | Santhera Pharmaceuticals (Schweiz) AG (CH) | 2009-06-24 | — | — | EP | disclosed |