SCHEMBL4146592

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4146596	1.00	ALDH1A1 (0.38)	ALDH1A1NPSR1KDRTP53AURKA
	SCHEMBL4141145	0.89	ALDH1A1 (0.37)	ALDH1A1KDRTP53AURKAAURKB
	SCHEMBL4141139	0.89	ALDH1A1 (0.37)	ALDH1A1KDRTP53AURKAAURKB
	SCHEMBL4146169	0.88	KDR (0.42)	KDRAURKAAURKBCHEK1TNFRSF1A
	SCHEMBL4146162	0.88	KDR (0.42)	KDRAURKAAURKBCHEK1TNFRSF1A
	SCHEMBL5027604	0.84	NPC1 (0.36)	ALDH1A1NPSR1TP53AURKAKDM4E
	SCHEMBL5027600	0.84	NPC1 (0.36)	ALDH1A1NPSR1TP53AURKAKDM4E
	SCHEMBL4149953	0.84	CHEK1 (0.46)	ALDH1A1NPSR1KDRKDM4EHPGD
	SCHEMBL4149958	0.84	CHEK1 (0.46)	ALDH1A1NPSR1KDRKDM4EHPGD
	SCHEMBL4136174	0.83	NPC1 (0.38)	ALDH1A1NPSR1AURKAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.