⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5077480 | 0.65 | — | — | |
| SCHEMBL6219705 | 0.62 | — | — | |
| SCHEMBL4156488 | 0.61 | — | — | |
| SCHEMBL14897928 | 0.60 | — | — | |
| SCHEMBL4148921 | 0.60 | — | — | |
| Bicarbonate SCHEMBL3962312 | 0.57 | — | — | |
| SCHEMBL16850625 | 0.56 | — | — | |
| SCHEMBL7596571 | 0.56 | — | — | |
| SCHEMBL2025314 | 0.48 | — | — | |
| Bicarbonate SCHEMBL28437232 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101497621-A | 1,5-dihydro-2H-pyrrol-2-one tricyclic derivatives having anti-infective activity | CPC BIOTECH S R L (IT) | 2009-08-05 | — | — | CN | claimed |
| US-20090192308-A1 | 1,5-DIHYDRO-2H-PYRROL-2-ONE TRICYCLIC DERIVATIVES HAVING ANTI-INFECTIVE ACTIVITY | CPC BIOTECH S. R.L. (IT) | 2009-07-30 | — | — | US | claimed |
| EP-2083012-A1 | 1,5-dihydro-2h-pyrrol-2-one tricyclic derivatives having pharmacological activity and processes for their preparation | CPC Biotech S.r.l. (IT) | 2009-07-29 | — | — | EP | claimed |
| CN-101497621-A | 1,5-dihydro-2H-pyrrol-2-one tricyclic derivatives having anti-infective activity | CPC BIOTECH S R L (IT) | 2009-08-05 | — | — | CN | disclosed |
| US-20090192308-A1 | 1,5-DIHYDRO-2H-PYRROL-2-ONE TRICYCLIC DERIVATIVES HAVING ANTI-INFECTIVE ACTIVITY | CPC BIOTECH S. R.L. (IT) | 2009-07-30 | — | — | US | disclosed |
| EP-2083012-A1 | 1,5-dihydro-2h-pyrrol-2-one tricyclic derivatives having pharmacological activity and processes for their preparation | CPC Biotech S.r.l. (IT) | 2009-07-29 | — | — | EP | disclosed |