⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16850625 | 0.65 | — | — | |
| SCHEMBL4147495 | 0.65 | — | — | |
| SCHEMBL6219705 | 0.62 | — | — | |
| SCHEMBL1805622 | 0.61 | — | — | |
| Water SCHEMBL27788635 | 0.60 | — | — | |
| SCHEMBL31367006 | 0.58 | KDM4E (0.31) | — | |
| SCHEMBL14741493 | 0.58 | TSHR (0.36) | — | |
| SCHEMBL468595 | 0.58 | — | — | |
| SCHEMBL8358110 | 0.58 | — | — | |
| SCHEMBL321783 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| CN-103724330-B | The effective combined utilization of monobactams antibiotic and beta-lactamase inhibitor | BASLIER PHARMACEUTICAL AG (CH) | 2015-08-19 | — | — | CN | disclosed |
| CN-104603125-A | 6-amino acid heteroaryl dihydropyrimidines for the treatment and prevention of hepatitis B virus infection | HOFFMANN LA ROCHE | 2015-05-06 | — | — | CN | disclosed |
| CN-102988362-B | Useful combinations of monobactam antibiotics with beta-lactamase inhibitors | BASILEA PHARMACEUTICA AG | 2014-11-05 | — | — | CN | disclosed |
| CN-103724330-A | Useful combinations of monobactam antibiotics with beta-lactamase inhibitors | BASILEA PHARMACEUTICA AG | 2014-04-16 | — | — | CN | disclosed |
| CN-102988362-A | Useful combinations of monobactam antibiotics with beta-lactamase inhibitors | BASILEA PHARMACEUTICA AG | 2013-03-27 | — | — | CN | disclosed |
| CN-101495536-B | Methods for site-specific pegylation | IPSEN PHARMA SAS | 2012-03-07 | — | — | CN | disclosed |
| CN-101495536-A | Methods for site-specific pegylation | SOD CONSEILS RECH APPLIC (FR) | 2009-07-29 | — | — | CN | disclosed |
| CN-101410111-A | Effective combined application of monocyclic lactam antibiotics and beta-lactamase inhibitor | BASILEA PHARMACEUTICA AG (CH) | 2009-04-15 | — | — | CN | disclosed |
| EP-1965798-A2 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007065288-A2 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2007-06-14 | — | — | WO | disclosed |
| US-4282235-A | Derivatives of thiazolidinecarboxylic acids and related acids | E. R. SQUIBB & SONS, INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4237134-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4237129-A | Derivatives of thiazolidinecarboxylic acids and related acids | E. R. SQUIBB & SONS, INC. (US) | 1980-12-02 | — | — | US | disclosed |
| US-4192878-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-03-11 | — | — | US | disclosed |