Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.42 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16295164 | 1.00 | FAAH (0.48) | FAAHTRPV1MAPTTBXAS1PTPN1 | |
| SCHEMBL4148731 | 1.00 | FAAH (0.48) | FAAHTRPV1MAPTTBXAS1PTPN1 | |
| SCHEMBL646382 | 1.00 | FAAH (0.48) | FAAHTRPV1MAPTTBXAS1PTPN1 | |
| SCHEMBL16293947 | 1.00 | FAAH (0.48) | FAAHTRPV1MAPTTBXAS1PTPN1 | |
| SCHEMBL3768374 | 1.00 | FAAH (0.48) | FAAHTRPV1MAPTTBXAS1PTPN1 | |
| SCHEMBL5403889 | 1.00 | FAAH (0.48) | FAAHTRPV1MAPTTBXAS1PTPN1 | |
| SCHEMBL16295185 | 1.00 | FAAH (0.48) | FAAHTRPV1MAPTTBXAS1PTPN1 | |
| SCHEMBL8158979 | 1.00 | FAAH (0.48) | FAAHTRPV1MAPTTBXAS1PTPN1 | |
| SCHEMBL8158977 | 1.00 | FAAH (0.48) | FAAHTRPV1MAPTTBXAS1PTPN1 | |
| SCHEMBL3485654 | 1.00 | FAAH (0.48) | FAAHTRPV1MAPTTBXAS1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4290966-A | Process for the preparation of traumatin | MERCK & CO., INC. (US) | 1981-09-22 | — | — | US | claimed |
| US-20090104705-A1 | Ascorbic acid conjugates | STATE OR OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY | 2009-04-23 | — | — | US | disclosed |
| WO-2006127695-A2 | ASCORBIC ACID CONJUGATES | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2006-11-30 | — | — | WO | disclosed |
| US-4290966-A | Process for the preparation of traumatin | MERCK & CO., INC. (US) | 1981-09-22 | — | — | US | disclosed |
| US-4290966-A | Process for the preparation of traumatin | MERCK & CO., INC. (US) | 1981-09-22 | — | — | US | disclosed |