Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | MAPT | P10636 | 10/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | HPGD | P15428 | 7/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489856 | 0.98 | ALDH1A1 (0.65) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL10711946 | 0.95 | ALDH1A1 (0.62) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL20922443 | 0.83 | CXCR2 (0.53) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL10714412 | 0.83 | ALDH1A1 (0.68) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL2179728 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL4140103 | 0.80 | MAPT (0.67) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL4090734 | 0.79 | ALDH1A1 (0.97) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL1887318 | 0.79 | ALDH1A1 (0.97) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL10720071 | 0.79 | MAPT (0.56) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL6315716 | 0.79 | CXCR2 (0.54) | ALDH1A1MAPTHSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-06-04 | — | — | US | disclosed |
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-06-04 | — | — | US | disclosed |
| EP-1802634-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | Compass Pharmaceuticals LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006044826-A2 | THIOPHENS AND THEIR USE AS ANTI-TUMOR AGENTS | COMPASS PHARMACEUTICALS LLC (US) | 2006-04-27 | — | — | WO | disclosed |
| US-4692461-A | PLANT PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143411-A1 | Thiophens and Their Use as Anti-Tumor Agents | TP53, BRDT, VHL | ALDH1A1 1202/4885MAPT 1629/4885HSD17B10 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.