Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.32 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 2/20 | 0.31 |
| ▸ | CDK8 | P49336 | 2/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28303592 | 0.75 | CCNT1 (0.50) | CDC7KDRMAPK1PARP15PARP14 | |
| SCHEMBL31657673 | 0.73 | MKNK1 (0.49) | CDC7MKNK1MKNK2 | |
| SCHEMBL3086806 | 0.73 | MAPK1 (0.48) | RIPK1KMT2AMAPK1ALDH1A1PARP15 | |
| SCHEMBL5755806 | 0.72 | MMP2 (0.47) | RIPK1CDK7 | |
| SCHEMBL5754638 | 0.72 | RET (0.45) | KDR | |
| Hydrochloric Acid SCHEMBL31747485 | 0.71 | MAPK1 (0.47) | RIPK1KMT2AMAPK1ALDH1A1PARP15 | |
| SCHEMBL4191442 | 0.70 | CDC7 (1.00) | CDC7CCNCCDK8 | |
| SCHEMBL27752657 | 0.70 | LCK (0.41) | KMT2AALDH1A1PARP15PARP14PARP10 | |
| SCHEMBL19133994 | 0.69 | CDC7 (0.70) | CDC7KDRMAPK1ALDH1A1MKNK1 | |
| SCHEMBL7176525 | 0.69 | MAPK14 (0.43) | MAPK1ALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009078498-A1 | BIARYLPYRAZOLE 4-CARBOXAMIDES AS CANNABINOID CB1 RECEPTOR LIGANDS | GREEN CROSS CORPORATION (KR) | 2009-06-25 | — | — | WO | disclosed |