Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.60 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.60 |
| ▸ | FKBP1A | P62942 | 9/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157014 | 1.00 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1FKBP1AKLK7KLK5 | |
| SCHEMBL4160039 | 0.86 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1FKBP1APDK2PDK4 | |
| SCHEMBL13741324 | 0.82 | GFER (0.57) | HSP90AA1HSP90AB1KLK7KLK5GFER | |
| SCHEMBL6788577 | 0.82 | FKBP1A (0.63) | FKBP1AKLK7KLK5 | |
| SCHEMBL6788581 | 0.82 | FKBP1A (0.63) | FKBP1AKLK7KLK5 | |
| SCHEMBL6787454 | 0.81 | FKBP1A (0.60) | FKBP1A | |
| SCHEMBL6787446 | 0.81 | FKBP1A (0.60) | FKBP1A | |
| SCHEMBL11443635 | 0.81 | FKBP1A (0.67) | FKBP1AKLK7KLK5 | |
| SCHEMBL19475037 | 0.81 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1PDK1PDK2PDK3 | |
| SCHEMBL28351585 | 0.81 | FKBP1A (0.67) | FKBP1AKLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | claimed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | HSP90AA1 2/4885HSP90AB1 1/4885FKBP1A 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.