Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 2/20 | 0.60 |
| ▸ | TACR3 | P29371 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.54 |
| ▸ | HTR2B | P41595 | 3/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9785745 | 0.93 | CYP2C9 (0.63) | SPRCYP2C9CYP2C19MAPK14HTR2B | |
| SCHEMBL4151901 | 0.88 | SPR (0.62) | SPRTACR3CYP2C9CYP2C19MAPK14 | |
| SCHEMBL4155107 | 0.83 | HSP90AA1 (0.50) | SPRHSP90AA1HSP90AB1 | |
| SCHEMBL4145949 | 0.83 | GRIN2D (0.63) | SPRCYP2C9CYP2C19MAPK14HTR2B | |
| SCHEMBL4143776 | 0.81 | CYP2C9 (0.54) | SPRCYP2C9CYP2C19MAPK14HTR2B | |
| SCHEMBL2729282 | 0.81 | CYP2C9 (0.60) | SPRCYP2C9CYP2C19MAPK14HTR2B | |
| SCHEMBL4143175 | 0.79 | HSP90AA1 (0.62) | SPRHSP90AA1HSP90AB1 | |
| SCHEMBL5820252 | 0.78 | CYP2C9 (0.77) | CYP2C9CYP2C19MAPK14HTR2BGRIN2D | |
| SCHEMBL4152644 | 0.78 | SPR (0.45) | SPRCYP2C9GRIN2BHSP90AA1HSP90AB1 | |
| SCHEMBL4155933 | 0.77 | SPR (0.52) | SPRGRIN1GRIN2BHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | claimed |
| EP-1879863-A1 | AMIDE RESORCINOL COMPOUNDS | Pfizer, Inc. (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006117669-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER INC. (US) | 2006-11-09 | — | — | WO | claimed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| EP-1879863-A1 | AMIDE RESORCINOL COMPOUNDS | Pfizer, Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117669-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER INC. (US) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | SPR 906/4885TACR3 3743/4885CYP2C9 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.