SCHEMBL4152018

SCHEMBL4152018

O=C(O)C(=C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4152660 0.98 THRB (0.52) THRB
SCHEMBL346291 0.94 THRB (0.52) THRB
SCHEMBL4160744 0.94 THRB (0.52) THRB
SCHEMBL870677 0.94 THRB (0.52) THRB
SCHEMBL15955385 0.91 THRB (0.48) THRB
SCHEMBL830695 0.89 THRB (0.52) THRB
SCHEMBL1502755 0.89 THRB (0.52) THRB
SCHEMBL6562727 0.89 THRB (0.52) THRB
SCHEMBL9943482 0.89 THRB (0.52) THRB
SCHEMBL29281938 0.89 THRB (0.52) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090212467-A1 Expandable Bladder PIRELLI PNEUMATICI S.P.A. (IT) 2009-08-27 US claimed
EP-1841576-A1 EXPANDABLE BLADDER Pirelli Tyre S.p.A. (IT) 2007-10-10 EP claimed
WO-2006079359-A1 EXPANDABLE BLADDER PIRELLI TYRE S.P.A. (IT) 2006-08-03 WO claimed
US-20090212467-A1 Expandable Bladder PIRELLI PNEUMATICI S.P.A. (IT) 2009-08-27 US disclosed
EP-1841576-A1 EXPANDABLE BLADDER Pirelli Tyre S.p.A. (IT) 2007-10-10 EP disclosed
WO-2006079359-A1 EXPANDABLE BLADDER PIRELLI TYRE S.P.A. (IT) 2006-08-03 WO disclosed