Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPR3 | P17342 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4152157 | 1.00 | TP53 (0.43) | TP53HPGDRECQLMAPTMEN1 | |
| SCHEMBL12462983 | 0.83 | HPGD (0.58) | TP53HPGDRECQLMAPTMEN1 | |
| SCHEMBL6394050 | 0.82 | JAK3 (0.48) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL4143822 | 0.82 | JAK3 (0.48) | MAPTMEN1KMT2AKDM4EHTT | |
| SCHEMBL14384562 | 0.77 | MEN1 (0.58) | HPGDMAPTMEN1KMT2ARAB9A | |
| Dyrene SCHEMBL20787720 | 0.74 | TSHR (0.49) | TP53HPGDRECQLMAPTMEN1 | |
| SCHEMBL20787721 | 0.74 | HPGD (0.59) | TP53HPGDRECQLMAPTMEN1 | |
| SCHEMBL12896253 | 0.73 | MAPT (0.61) | HPGDRECQLMAPTMEN1KMT2A | |
| SCHEMBL12896256 | 0.73 | MAPT (0.61) | HPGDRECQLMAPTMEN1KMT2A | |
| SCHEMBL4134442 | 0.73 | MAPT (0.46) | HPGDMAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090074820-A1 | AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF | L'OREAL (FR) | 2009-03-19 | — | — | US | disclosed |
| US-20050008588-A1 | Aminoarylvinyl-s-triazine compounds and uses thereof | L'OREAL (FR) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050008588-A1 | Aminoarylvinyl-s-triazine compounds and uses thereof | TYR, AAAS, ALAD | TP53 1686/4885HPGD 1021/4885RECQL 1281/4885 |
| US-20090074820-A1 | AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF | TYR, AAAS, ALAD | TP53 1661/4885HPGD 1008/4885RECQL 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.