Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 4/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1179747 | 0.84 | TDP1 (0.62) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL29396391 | 0.84 | TDP1 (0.62) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL15814169 | 0.82 | TDP1 (0.42) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL28215127 | 0.78 | TDP1 (0.56) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL9747035 | 0.78 | TDP1 (0.56) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL29625716 | 0.77 | NCEH1 (0.64) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL4594864 | 0.77 | NCEH1 (0.64) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL17372898 | 0.76 | SMN1; SMN2 (0.50) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL1961457 | 0.76 | TDP1 (0.63) | TDP1L3MBTL1KDM4EPOLBCTDSP1 | |
| SCHEMBL11798976 | 0.75 | ALDH1A1 (0.57) | TDP1L3MBTL1KDM4EPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021897-A1 | RING COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-26 | — | — | US | disclosed |
| EP-2399918-A1 | RING COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2011-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021897-A1 | RING COMPOUND | NR4A2, NR4A1, NR0B1 | TDP1 4499/4885L3MBTL1 4352/4885KDM4E 2123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.