Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.93 |
| ▸ | QPCT | Q16769 | 2/20 | 0.81 |
| ▸ | XDH | P47989 | 9/20 | 0.80 |
| ▸ | MAOB | P27338 | 7/20 | 0.74 |
| ▸ | MAOA | P21397 | 5/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | TP53 | P04637 | 4/20 | 0.74 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.74 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151838 | 0.96 | ABCB1 (1.00) | ABCB1QPCTXDHMAOBMAOA | |
| SCHEMBL4155804 | 0.96 | ABCB1 (1.00) | ABCB1QPCTXDHMAOBMAOA | |
| SCHEMBL4139761 | 0.96 | ABCB1 (1.00) | ABCB1QPCTXDHMAOBMAOA | |
| SCHEMBL4156208 | 0.96 | ABCB1 (1.00) | ABCB1QPCTXDHMAOBMAOA | |
| SCHEMBL4155808 | 0.96 | ABCB1 (1.00) | ABCB1QPCTXDHMAOBMAOA | |
| SCHEMBL4152249 | 0.96 | ABCB1 (1.00) | ABCB1QPCTXDHMAOBMAOA | |
| SCHEMBL4156163 | 0.96 | ABCB1 (1.00) | ABCB1QPCTXDHMAOBMAOA | |
| SCHEMBL4143778 | 0.92 | ABCB1 (0.91) | ABCB1QPCTXDHMAOBMAOA | |
| SCHEMBL4162791 | 0.92 | ABCB1 (0.91) | ABCB1QPCTXDHMAOBMAOA | |
| SCHEMBL1421453 | 0.91 | XDH (0.78) | ABCB1QPCTXDHMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710097-B2 | Flavonoid dimers and methods of making and using such | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2014-04-29 | — | — | US | disclosed |
| US-20090197943-A1 | Flavonoid Dimers and Methods of Making and Using Such | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197943-A1 | Flavonoid Dimers and Methods of Making and Using Such | ABCB1, ABCC1, SLC47A2 | ABCB1 1/4885QPCT 291/4885XDH 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.