Thymine

Thymine

SCHEMBL4152636

Cc1c[nH]c(=O)nc1O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4512381 0.76
SCHEMBL4016272 0.76
SCHEMBL10402389 0.73
SCHEMBL22008 0.73
SCHEMBL1231792 0.73 ATAD2 (0.37)
SCHEMBL10402388 0.73
SCHEMBL546152 0.73
SCHEMBL27533747 0.73
SCHEMBL15456758 0.72 ATAD2 (0.33)
Water SCHEMBL28196064 0.71 ATAD2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0132127-B1 CYCLIC UREA CONDENSATES, TEXTILE AND PAPER TREATING COMPOSITIONS AND NOVEL CYCLIC UREAS SEQUA CHEMICALS INC. (US) 1993-02-03 EP claimed
WO-2022250155-A1 ANTISENSE NUCLEIC ACID 住友ファーマ株式会社 2022-12-01 WO disclosed
WO-2022097727-A1 REGULATOR FOR EXPRESSION AND/OR FUNCTION OF RPS25 GENE 住友ファーマ株式会社 2022-05-12 WO disclosed
EP-2753607-B1 BICYCLO[6.1.0]NON-4-YNE REAGENTS FOR CHEMICAL MODIFICATION OF OLIGONUCLEOTIDES BERRY AND ASSOCIATES INC (US) 2016-04-13 EP disclosed
EP-1828146-B1 SUBSTITUTED N-HETEROCYCLIC COMPOUNDS AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS ABBVIE DEUTSCHLAND (DE) 2014-11-05 EP disclosed
US-20130066063-A1 BICYCLO[6.1.0]NON-4-YNE REGENTS FOR CHEMICAL MODIFICATION OF OLIGONUCLEOTIDES BERRY AND ASSOCIATES, INC. 2013-03-14 US disclosed
US-20090054449-A1 Substituted N-heterocyclic Compounds and Their Use as Dopamine D3 Receptor Ligands ABBOTT GMBH & CO. KG (DE) 2009-02-26 US disclosed
US-7326783-B2 Pharmaceutical composition comprising antisense-nucleic acid for prevention and/or treatment of neuronal injury, degeneration and cell death and for the treatment of neoplasms BIOGNOSTIK GESELLSCHAFT FUR BIOMOLEKULARE DIAGNOSTIK MBH (DE) 2008-02-05 US disclosed
EP-1601659-B1 PYRIMIDIN-2-ONE COMPOUNDS AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS ABBOTT GMBH & CO KG (DE) 2008-01-16 EP disclosed
EP-1828146-A1 SUBSTITUTED N-HETEROCYCLIC COMPOUNDS AND THEIR USE AS DOPAMINE D3 RECEPTOR LIGANDS Abbott GmbH & Co. KG (DE) 2007-09-05 EP disclosed
US-20030008580-A1 High-wet-bulk cellulosic fibers WEYERHAEUSER COMPANY 2003-01-09 US disclosed
US-6207278-B1 CROSSLINKING CELLULOSE WITH GLYOXAL, PROPYLENE GLYCOL, ALUMINUM SULFATE AND CITRIC ACID WEYERHAEUSER COMPANY 2001-03-27 US disclosed
EP-0261878-B1 Coating binder additive SEQUA CHEMICALS INC (US) 1993-11-18 EP disclosed
EP-0132127-B1 CYCLIC UREA CONDENSATES, TEXTILE AND PAPER TREATING COMPOSITIONS AND NOVEL CYCLIC UREAS SEQUA CHEMICALS INC. (US) 1993-02-03 EP disclosed
US-4837087-A BLOCKED GLYOXAL RESIN MIXED WITH VINYL OR ACRYLIC WATER SOLUBLE RESIN SEQUA CHEMICALS INC. (US) 1989-06-06 US disclosed
EP-0261878-A2 Coating binder additive SEQUA CHEMICALS INC. (US) 1988-03-30 EP disclosed
US-4695606-A BLOCKED GLYOXAL RESIN MIXED WITH WATER SOLUBLE POLYMER SUN CHEMICAL CORPORATION (US) 1987-09-22 US disclosed
US-4505712-A Cyclic urea/glyoxal/polyol condensates and their use in treating textile fabrics and paper SUN CHEMICAL CORPORATION (US) 1985-03-19 US disclosed
EP-0132127-A2 Cyclic urea condensates, textile and paper treating compositions and novel cyclic ureas SEQUA CHEMICALS INC. (US) 1985-01-23 EP disclosed
US-4455416-A INSOLUBILIZERS SUN CHEMICAL CORPORATION (US) 1984-06-19 US disclosed