Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Caprolactam SCHEMBL4145590 | 0.86 | DPP4 (0.38) | DPP4DPP8DPP7 | |
| Caprolactam SCHEMBL388930 | 0.85 | DPP4 (0.51) | DPP4DPP8DPP7 | |
| Caprolactam SCHEMBL1846964 | 0.72 | DPP4 (0.50) | DPP4DPP8DPP7 | |
| SCHEMBL4152645 | 0.66 | DPP4 (0.68) | DPP4DPP8DPP7 | |
| SCHEMBL29196914 | 0.61 | DPP4 (0.55) | DPP4DPP8DPP7 | |
| Caprolactam SCHEMBL4157306 | 0.59 | FKBP5 (0.42) | DPP4DPP8 | |
| SCHEMBL28435927 | 0.57 | DPP4 (0.45) | DPP4DPP8 | |
| SCHEMBL21565165 | 0.57 | DPP4 (0.53) | DPP4DPP8DPP7 | |
| SCHEMBL12187861 | 0.56 | HDAC1 (0.40) | DPP4 | |
| Caprolactam SCHEMBL5422431 | 0.56 | CRBN (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | MERCK & CO., INC. | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | DPP4, DPP3, DPP7 | DPP4 1/4885DPP8 5/4885DPP7 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.