Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953853 | 0.83 | MAPT (0.62) | MAPTALDH1A1L3MBTL1BCHEACHE | |
| SCHEMBL8251271 | 0.81 | KMT2A (0.63) | MAPTALDH1A1L3MBTL1TAAR1SMN1; SMN2 | |
| SCHEMBL5775605 | 0.81 | MAPT (0.59) | MAPTALDH1A1L3MBTL1BCHEACHE | |
| SCHEMBL764662 | 0.81 | POLB (0.68) | MAPTALDH1A1L3MBTL1TAAR1GAA | |
| SCHEMBL4152933 | 0.81 | MAPT (0.59) | MAPTALDH1A1L3MBTL1TAAR1SMN1; SMN2 | |
| SCHEMBL1409656 | 0.80 | MAPT (0.66) | MAPTALDH1A1L3MBTL1TAAR1GAA | |
| SCHEMBL20245304 | 0.79 | POLB (0.58) | MAPTALDH1A1L3MBTL1TAAR1SMN1; SMN2 | |
| SCHEMBL4086221 | 0.78 | TDP1 (0.59) | MAPTALDH1A1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL10916539 | 0.78 | MAPT (0.63) | MAPTALDH1A1L3MBTL1BCHEACHE | |
| SCHEMBL17963199 | 0.76 | ALDH1A1 (0.79) | MAPTALDH1A1L3MBTL1TAAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170847-A1 | Imidazopyridine Derivatives Inhibiting Protein Kinase Activity, Method for the Preparation Thereof and Pharmaceutical Composition Containing Same | YUYU PHARMA, INC. (KR) | 2009-07-02 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170847-A1 | Imidazopyridine Derivatives Inhibiting Protein Kinase Activity, Method for the Preparation Thereof and Pharmaceutical Composition Containing Same | GSK3B, GSK3A, MAP3K3 | MAPT 119/4885ALDH1A1 4274/4885L3MBTL1 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.