SCHEMBL4153372

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4153365	1.00	POLB (0.37)	POLBTYK2JAK1NTRK1CTSL
	SCHEMBL4150256	0.89	POLB (0.40)	POLBNTRK1CHEK1LMNASMN1; SMN2
	SCHEMBL4150244	0.89	POLB (0.40)	POLBNTRK1CHEK1LMNASMN1; SMN2
	SCHEMBL4152203	0.89	MAPT (0.45)	POLBLMNASMN1; SMN2
	SCHEMBL4152208	0.89	MAPT (0.45)	POLBLMNASMN1; SMN2
	SCHEMBL4150248	0.89	POLB (0.35)	POLBCTSLNFE2L2CHEK1NPC1
	SCHEMBL6428608	0.89	MAPK1 (0.35)	POLBNTRK1CTSLCHEK1NPC1
	SCHEMBL6426050	0.89	POLB (0.39)	POLBCHEK1KDRABL1CDK2
	SCHEMBL4137384	0.88	NFE2L2 (0.38)	CTSLNFE2L2CHEK1NPC1RAB9A
	SCHEMBL4137389	0.88	NFE2L2 (0.38)	CTSLNFE2L2CHEK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.