Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Isopropyl Palmitate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.92 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | PRKCA | P17252 | 3/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
| ▸ | DGKA | P23743 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Myristate SCHEMBL1821126 | 1.00 | LMNA (0.92) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| Isopropyl Palmitate SCHEMBL1133116 | 0.96 | LMNA (1.00) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL43528 | 0.96 | LMNA (1.00) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL317355 | 0.96 | LMNA (1.00) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL126208 | 0.96 | LMNA (1.00) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| Isopropyl Palmitate SCHEMBL7743 | 0.96 | LMNA (1.00) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL1173030 | 0.96 | LMNA (1.00) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| Isopropyl Palmitate SCHEMBL22578002 | 0.96 | LMNA (1.00) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL29523 | 0.96 | LMNA (1.00) | LMNAMAPTMAPK1ALDH1A1PRKCA | |
| SCHEMBL1278398 | 0.96 | LMNA (1.00) | LMNAMAPTMAPK1ALDH1A1PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106106524-A | A kind of compositions preventing and treating beet armyworm and preparation method thereof | 殷佩琼 | 2016-11-16 | — | — | CN | claimed |
| CN-106106524-A | A kind of compositions preventing and treating beet armyworm and preparation method thereof | 殷佩琼 | 2016-11-16 | — | — | CN | disclosed |
| US-20090085256-A1 | IMAGE FORMING METHOD AND APPARATUS | FUJIFILM CORPORATION (JP) | 2009-04-02 | — | — | US | disclosed |
| US-20090017120-A1 | Phase stable lecithin organogel composition | HUMCO HOLDING GROUP, INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-6110501-A | A TABLET THAT UTILIZES MICROCAPSULES WHEREIN AN ACTIVE SUBSTANCE FORMS THE CORE OF THE MICROCAPSULE AND OTHER CHEMICAL AGENTS(SEEDS) ARE DISPERSED THROUGHOUT THE MICROCAPSULE SHELL TO STRENGTHEN THE SHELL | VERION INC. (US) | 2000-08-29 | — | — | US | disclosed |