⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2050055 | 0.71 | — | — | |
| SCHEMBL2050780 | 0.71 | — | — | |
| SCHEMBL9899330 | 0.70 | — | — | |
| SCHEMBL10437480 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL2048085 | 0.67 | — | — | |
| SCHEMBL2044396 | 0.67 | — | — | |
| SCHEMBL2044981 | 0.67 | — | — | |
| SCHEMBL9899523 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL17257042 | 0.67 | TSHR (0.32) | — | |
| SCHEMBL17257045 | 0.67 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618216-B1 | Method of making silane coupled polymers | BRIDGESTONE CORPORATION (JP) | 2013-12-31 | — | — | US | disclosed |
| US-8314183-B2 | Silane coupled polymers | BRIDGESTONE CORPORATION (JP) | 2012-11-20 | — | — | US | disclosed |
| US-20090163675-A1 | SILANE COUPLED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2009-06-25 | — | — | US | disclosed |