Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | RAD1 | O60671 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | LTA | P01374 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657224 | 0.80 | CYP3A4 (0.54) | TDP1MAPK1CYP3A4TRPA1RAD1 | |
| SCHEMBL8853900 | 0.77 | MAPK1 (0.58) | TDP1MAPK1CYP3A4TRPA1PTGS1 | |
| SCHEMBL5657231 | 0.77 | CYP3A4 (0.50) | TDP1MAPK1CYP3A4TRPA1TSHR | |
| SCHEMBL28571018 | 0.75 | TDP1 (0.37) | TDP1MAPK1CYP3A4TRPA1RAD1 | |
| SCHEMBL10396139 | 0.75 | CA1 (0.39) | TDP1MAPK1CYP3A4TRPA1PTGS1 | |
| SCHEMBL30932296 | 0.74 | MAPK1 (0.52) | TDP1MAPK1CYP3A4TRPA1PTGS1 | |
| SCHEMBL8348200 | 0.74 | MAPK1 (0.52) | TDP1MAPK1CYP3A4TRPA1PTGS1 | |
| SCHEMBL10885567 | 0.73 | CDK2 (0.37) | TDP1MAPK1CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL182964 | 0.71 | CYP3A4 (0.47) | TDP1MAPK1CYP3A4TRPA1PTGS1 | |
| SCHEMBL11191075 | 0.71 | CYP3A4 (0.60) | TDP1MAPK1CYP3A4TRPA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1609362-B1 | Non-systemic control of parasites | BAYER IP GMBH (DE) | 2015-03-18 | — | — | EP | disclosed |
| US-8728507-B2 | Non-systemic control of parasites | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-20 | — | — | US | disclosed |
| US-7517535-B2 | Non-systemic control of parasites | BAYER ANIMAL HEALTH GMBH (DE) | 2009-04-14 | — | — | US | disclosed |
| US-20080108671-A1 | NON-SYSTEMIC CONTROL OF PARASITES | BAYER HEALTHCARE AG (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20080108670-A1 | NON-SYSTEMIC CONTROL OF PARASITES | BAYER HEALTHCARE AG (DE) | 2008-05-08 | — | — | US | disclosed |
| US-20060276517-A1 | Non-systemic control of parasites | BAYER HEALTHCARE AG (DE) | 2006-12-07 | — | — | US | disclosed |
| EP-1609362-A2 | Non-systemic control of parasites | Bayer HealthCare AG (DE) | 2005-12-28 | — | — | EP | disclosed |
| EP-0682869-B1 | Non-systemic control of parasites | BAYER HEALTHCARE AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| US-20050222217-A1 | Non-systemic control of parasites | BAYER HEALTHCARE AG (DE) | 2005-10-06 | — | — | US | disclosed |
| US-6896891-B2 | Non-systemic control of parasites | BAYER AKTIENGESELLSCHAFT (DE) | 2005-05-24 | — | — | US | disclosed |
| US-6329374-B1 | CONTROLLING PARASITES SUCH AS LICE AND FLEAS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-11 | — | — | US | disclosed |
| US-20010044456-A1 | Antagonists/agonists of nicotinergic acetylcholine receptors in insects; imidacloprid; such as fleas, lice and flies | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2001-11-22 | — | — | US | disclosed |
| US-20010041723-A1 | Non-systemic control of parasites | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2001-11-15 | — | — | US | disclosed |
| US-20010027201-A1 | Non-systemic control of parasites | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2001-10-04 | — | — | US | disclosed |
| US-20010021716-A1 | Non-systemic control of parasites | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2001-09-13 | — | — | US | disclosed |
| US-6232328-B1 | CONTACTING FLEAS AND LIC ON A HUMAN OR ANIMALS WITH AN IMIDAZOLINIUM COMPOUND TO KILL FLIES AND INSECTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-15 | — | — | US | disclosed |
| EP-0682869-A1 | Non-systemic control of parasites | BAYER AG (DE) | 1995-11-22 | — | — | EP | disclosed |
| US-5294445-A | Animal collars | BAYER AKTIENGESELLSCHAFT (DE) | 1994-03-15 | — | — | US | disclosed |
| EP-0569791-A2 | Shaped bodies for the control of ektoparasites on animals | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |
| EP-0528303-A1 | Shaped bodies for the control of undesired organisms | BAYER AG (DE) | 1993-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276517-A1 | Non-systemic control of parasites | CHRNG, CHRNA1, CHRM3 | TDP1 3485/4885MAPK1 2750/4885CYP3A4 1573/4885 |
| US-20080108671-A1 | NON-SYSTEMIC CONTROL OF PARASITES | CHRNG, CHRNA1, CHRM3 | TDP1 3485/4885MAPK1 2750/4885CYP3A4 1573/4885 |
| US-20010021716-A1 | Non-systemic control of parasites | CHRNG, CHRNA1, CHRM3 | TDP1 3485/4885MAPK1 2750/4885CYP3A4 1573/4885 |
| US-20050222217-A1 | Non-systemic control of parasites | CHRNG, CHRNA1, CHRM3 | TDP1 3485/4885MAPK1 2750/4885CYP3A4 1573/4885 |
| US-20080108670-A1 | NON-SYSTEMIC CONTROL OF PARASITES | CHRNG, CHRNA1, CHRM3 | TDP1 3485/4885MAPK1 2750/4885CYP3A4 1573/4885 |
| US-20010027201-A1 | Non-systemic control of parasites | CHRNG, CHRNA1, CHRM3 | TDP1 3485/4885MAPK1 2750/4885CYP3A4 1573/4885 |
| US-20010044456-A1 | Antagonists/agonists of nicotinergic acetylcholine receptors in insects; imidacloprid; such as fleas, lice and flies | CHRNG, CHRNE, CHRNA1 | TDP1 3420/4885MAPK1 1979/4885CYP3A4 1238/4885 |
| US-20010041723-A1 | Non-systemic control of parasites | CHRNG, CHRNA1, CHRM3 | TDP1 3485/4885MAPK1 2750/4885CYP3A4 1573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.