SCHEMBL182964

SCHEMBL182964

O=C=Nc1ccc(S(=O)(=O)N=C=O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.47
TSHR P16473 1/20 0.47
CA2 P00918 2/20 0.41
CA1 P00915 1/20 0.41
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TRPA1 O75762 1/20 0.37
EPHX2 P34913 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
CYP2C19 P33261 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
F2 P00734 2/20 0.31
PRSS1 P07477 2/20 0.31
PRSS2 P07478 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5656809 0.94 CYP3A4 (0.42) CYP3A4TSHRCA2CA1MAPK1
SCHEMBL5652661 0.89 CYP3A4 (0.67) CYP3A4TSHRCA2CA1MAPK1
SCHEMBL5653955 0.87 F2 (0.37) CYP3A4CYP1A2CYP2D6MAPTCYP2C9
SCHEMBL5654352 0.86 CA1 (0.59) CYP3A4TSHRCA2CA1TDP1
SCHEMBL7180551 0.80 CYP3A4 (0.52) CYP3A4TSHRCA2CA1MAPK1
SCHEMBL278353 0.80 CYP3A4 (0.52) CYP3A4TSHRCA2CA1MAPK1
SCHEMBL11612784 0.80 CYP3A4 (0.44) CYP3A4TSHRCA2CA1MAPK1
SCHEMBL1479252 0.78 CYP3A4 (0.39) CYP3A4TSHRCA2CA1MAPK1
SCHEMBL8470065 0.77 MAPK1 (0.59) CYP3A4MAPK1TDP1TRPA1MAPT
SCHEMBL10936908 0.77 CYP3A4 (0.41) CYP3A4TSHRCA2CA1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2016 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11745444-B2 Simultaneous optimization of fiber sizing in-line with the pultrusion process BASF SE (DE) 2023-09-05 US claimed
CN-113661190-B Laminated component comprising an anti-slip and waterproof outer layer and method for the production thereof 科思创有限公司 2023-08-01 CN claimed
EP-4179130-A1 METHODS OF REMOVING DEPOSITS FROM A SURFACE Angara Global Limited (GB) 2023-05-17 EP claimed
CN-112292243-B Wooden composite product 巴斯夫欧洲公司 2023-05-16 CN claimed
CN-111670112-B Simultaneous optimization of fiber sizing in-line with pultrusion process 巴斯夫欧洲公司 2022-12-20 CN claimed
CN-114698636-A Weeding composition, preparation method and application thereof 江苏龙灯化学有限公司 2022-07-05 CN claimed
CN-114668001-A Herbicide composition, preparation method and application thereof 江苏龙灯化学有限公司 2022-06-28 CN claimed
EP-4007783-A1 PULTRUSION PROCESSES FOR PRODUCING FIBER REINFORCED POLYURETHANE COMPOSITIONS AND POLYURETHANE-FORMING REACTION MIXTURES SUITABLE FOR USE IN SUCH PROCESSES Covestro LLC (US) 2022-06-08 EP claimed
CN-114206972-A Pultrusion process for preparing fiber reinforced polyurethane composites and polyurethane forming reaction mixtures suitable for use in such process 科思创有限公司 2022-03-18 CN claimed
EP-3947493-A1 LAMINATED PARTS CONTAINING A SLIP RESISTANT AND WATER RESISTANT OUTER LAYER AND METHODS FOR THEIR PRODUCTION Covestro LLC (US) 2022-02-09 EP claimed
US-20060235100-A1 Polyurethane foams made with vegetable oil hydroxylate, polymer polyol and aliphatic polyhydroxy alcohol BAYER MATERIALSCIENCE LLC 2006-10-19 US claimed
EP-1712576-A1 Polyurethane foams made with alkoxylated vegetable oil hydroxylate Bayer MaterialScience LLC (US) 2006-10-18 EP claimed
EP-1712578-A1 Polyurethane foams made with vegetable oil hydroxylate, polymer polyol and aliphatic polyhydroxy alcohol Bayer MaterialScience LLC (US) 2006-10-18 EP claimed
US-20060229375-A1 Polyurethane foams made with alkoxylated vegetable oil hydroxylate BAYER MATERIALSCIENCE LLC 2006-10-12 US claimed
US-20060205909-A1 Polyester polyols for polyurethane adhesives O'BRIEN MICHAEL E 2006-09-14 US claimed
EP-1556428-A2 FAST CURING COMPOSITIONS TYCO HEALTHCARE GROUP LP (US) 2005-07-27 EP claimed
US-6894140-B2 Fast curing compositions TYCO HEALTHECARE GROPU LP (US) 2005-05-17 US claimed
WO-2004083274-A1 POLYESTER POLYOLS FOR POLYURETHANE ADHESIVES STEPAN COMPANY (US) 2004-09-30 WO claimed
US-20040115229-A1 adhesive composition comprising at least one NCO-terminated hydrophilic urethane prepolymer; applying the adhesive composition over a defect in lung tissue COVIDIEN LP 2004-06-17 US claimed
WO-2004039323-A2 FAST CURING COMPOSITIONS TYCO HEALTHCARE GROUP LP (US) 2004-05-13 WO claimed