Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4150960 | 0.85 | APP (0.38) | APPNPC1ALDH1A1PKMRAB9A | |
| SCHEMBL4152917 | 0.82 | APP (0.35) | APPNPC1ALDH1A1PKMRAB9A | |
| SCHEMBL5516840 | 0.82 | APP (0.35) | APPNPC1ALDH1A1PKMRAB9A | |
| SCHEMBL13453287 | 0.79 | APP (0.69) | APP | |
| SCHEMBL4154941 | 0.79 | APP (0.69) | APP | |
| SCHEMBL5048522 | 0.75 | APP (0.58) | APPNPC1ALDH1A1PKMRAB9A | |
| SCHEMBL913532 | 0.75 | APP (0.58) | APPNPC1ALDH1A1PKMRAB9A | |
| SCHEMBL4152910 | 0.73 | APP (0.63) | APP | |
| SCHEMBL4150959 | 0.73 | APP (0.63) | APP | |
| SCHEMBL2817233 | 0.72 | APP (0.62) | APPNPC1ALDH1A1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893245-A4 | RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS | UNIV PENNSYLVANIA (US) | 2009-06-24 | — | — | EP | disclosed |
| EP-1893245-A2 | RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS | The Trustees of the University of Pennsylvania (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007002540-A2 | RADIOLABELED-PEGYLATION OF LIGANDS FOR USE AS IMAGING AGENTS | KUNG HANK F (US) | 2007-01-04 | — | — | WO | disclosed |