Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 7/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151567 | 0.80 | HTT (0.60) | HTTBRD4AVPR1AAVPR2BRD2 | |
| SCHEMBL5113889 | 0.79 | HTT (0.52) | HTTBRD4AVPR1AAVPR2BRD2 | |
| SCHEMBL7332664 | 0.71 | HTT (0.49) | HTTBRD4AVPR1AAVPR2BRD2 | |
| SCHEMBL4145691 | 0.69 | AVPR1A (0.61) | AVPR1AAVPR2OXTRALDH1A1POLB | |
| SCHEMBL4150867 | 0.67 | IDH1 (0.62) | AVPR1AAVPR2 | |
| SCHEMBL7337085 | 0.65 | AVPR2 (0.63) | AVPR1AAVPR2OXTR | |
| SCHEMBL5114252 | 0.64 | HTT (0.50) | HTTBRD4ALDH1A1LMNANPSR1 | |
| SCHEMBL4144847 | 0.63 | AVPR2 (0.52) | AVPR1AAVPR2OXTRALDH1A1POLB | |
| SCHEMBL7338077 | 0.61 | AVPR2 (0.77) | AVPR1AAVPR2OXTRALDH1A1 | |
| Formaldehyde SCHEMBL6355613 | 0.61 | AVPR2 (0.51) | AVPR1AAVPR2OXTRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227565-A1 | Biphenyl Vasopressin Agonists | WYETH (US) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227565-A1 | Biphenyl Vasopressin Agonists | AVPR2, AVPR1B, SSTR3 | HTT 1517/4885BRD4 1235/4885AVPR1A 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.