SCHEMBL4155288

SCHEMBL4155288

C=CCON=CC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9975266 1.00
SCHEMBL2533959 0.77 ALDH1A1 (0.38)
SCHEMBL7595015 0.74
SCHEMBL5477666 0.74
SCHEMBL27847356 0.74
SCHEMBL18785496 0.74
SCHEMBL18785502 0.74
SCHEMBL12831512 0.73
SCHEMBL680066 0.73
SCHEMBL1550097 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090105292-A9 Glucocorticoid Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED (US) 2009-04-23 US claimed
US-20070281959-A1 Glucocorticoid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 2007-12-06 US claimed
EP-1718653-A1 GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY Ligand Pharmaceuticals Inc. (US) 2006-11-08 EP claimed
WO-2005082909-A1 GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY LIGAND PHARMACEUTICALS INCORPORATED (US) 2005-09-09 WO claimed
CN-1095461-C Synthetic method for trifluoroacetyl acetophenone oxine and its derivative SHANGHAI INST ORGANIC CHEM (CN) 2002-12-04 CN claimed
EP-0085028-B1 N-PHENYLSULFONYL-N'-PYRIMIDINYL AND TRIAZINYL UREAS CIBA-GEIGY AG (CH) 1987-03-25 EP claimed
EP-0075821-B1 N-SUBSTITUTED CARBON AMIDES, PROCESS FOR THEIR PREPARATION AND FUNGICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1985-01-02 EP claimed
EP-0075821-A2 N-substituted carbon amides, process for their preparation and fungicides containing them BASF Aktiengesellschaft (DE) 1983-04-06 EP claimed
CN-114591197-A Process method for continuously synthesizing oxime ether 浙江圣安化工股份有限公司 2022-06-07 CN disclosed
US-20090105292-A9 Glucocorticoid Receptor Modulator Compounds and Methods LIGAND PHARMACEUTICALS INCORPORATED (US) 2009-04-23 US disclosed
US-20070281959-A1 Glucocorticoid receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 2007-12-06 US disclosed
EP-1718653-A1 GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY Ligand Pharmaceuticals Inc. (US) 2006-11-08 EP disclosed
WO-2005082909-A1 GLUCOCORTICOID RECEPTOR MODULATOR COMPOUNDS AND METHODS- UTILITY LIGAND PHARMACEUTICALS INCORPORATED (US) 2005-09-09 WO disclosed
US-5254717-A Imino-substituted phenyl derivatives, the preparation thereof and fungicides containing these BASF AKTIENGESELLSCHAFT (DE) 1993-10-19 US disclosed
US-4726836-A PREEMERGENCE, POSTEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1988-02-23 US disclosed
US-4648899-A N-phenylsulfonyl-N'-triazinylureas CIBA-GEIGY CORPORATION (US) 1987-03-10 US disclosed
US-4618363-A N-phenylsulfonyl-N'-triazinylureas CIBA-GEIGY CORPORATION (US) 1986-10-21 US disclosed
EP-0085028-A2 N-Phenylsulfonyl-N'-pyrimidinyl and triazinyl ureas CIBA-GEIGY AG (CH) 1983-08-03 EP disclosed
EP-0075821-A2 N-substituted carbon amides, process for their preparation and fungicides containing them BASF Aktiengesellschaft (DE) 1983-04-06 EP disclosed
EP-0075821-A2 N-substituted carbon amides, process for their preparation and fungicides containing them BASF Aktiengesellschaft (DE) 1983-04-06 EP disclosed