Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | POLH | Q9Y253 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | P4HB | P07237 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4166839 | 1.00 | ABCB1 (0.63) | ABCB1ADORA3POLHCYP3A4CYP2D6 | |
| SCHEMBL4169975 | 1.00 | ABCB1 (0.63) | ABCB1ADORA3POLHCYP3A4CYP2D6 | |
| SCHEMBL4167855 | 1.00 | ABCB1 (0.63) | ABCB1ADORA3POLHCYP3A4CYP2D6 | |
| SCHEMBL4162087 | 1.00 | ABCB1 (0.63) | ABCB1ADORA3POLHCYP3A4CYP2D6 | |
| SCHEMBL4163581 | 1.00 | ABCB1 (0.63) | ABCB1ADORA3POLHCYP3A4CYP2D6 | |
| SCHEMBL4155185 | 1.00 | ABCB1 (0.63) | ABCB1ADORA3POLHCYP3A4CYP2D6 | |
| SCHEMBL4161844 | 1.00 | ABCB1 (0.63) | ABCB1ADORA3POLHCYP3A4CYP2D6 | |
| SCHEMBL4161068 | 1.00 | ABCB1 (0.63) | ABCB1ADORA3POLHCYP3A4CYP2D6 | |
| SCHEMBL4165973 | 0.99 | ABCB1 (0.64) | ABCB1ADORA3POLHCYP3A4CYP2D6 | |
| SCHEMBL4163413 | 0.94 | ABCB1 (0.57) | ABCB1ADORA3POLHCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | ABCB1 1605/4885ADORA3 2776/4885POLH 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.