SCHEMBL4155579

SCHEMBL4155579

CCc1ccc(O)c(OC)c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.47
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HSD17B10 Q99714 1/20 0.44
METAP2 P50579 1/20 0.43
TRPV1 Q8NER1 3/20 0.42
POLB P06746 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
HTT P42858 1/20 0.40
TPMT P51580 3/20 0.39
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
PPARA Q07869 1/20 0.38
PRKCI P41743 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30803084 0.83 KDM4E (0.52) KDM4EALDH1A1HSD17B10CA12CA1
SCHEMBL13835746 0.83 KDM4E (0.52) KDM4EALDH1A1HSD17B10CA12CA1
SCHEMBL13888143 0.82 TDP1 (0.50) KDM4EALDH1A1HSD17B10METAP2CA12
SCHEMBL6357203 0.82 TDP1 (0.46) DRD2KDM4EALDH1A1HSD17B10METAP2
SCHEMBL20018063 0.81 ALDH1A1 (0.71) KDM4EALDH1A1HSD17B10METAP2CA12
Hydrochloric Acid SCHEMBL9876725 0.81 TDP1 (0.49) KDM4EALDH1A1HSD17B10METAP2CA12
SCHEMBL12504376 0.79 TRPV1 (0.43) DRD2TRPV1POLBCA12CA1
SCHEMBL28902668 0.78 KDM4E (0.47) KDM4EALDH1A1HSD17B10POLBCA12
SCHEMBL31746160 0.78 TDP1 (0.53) KDM4EALDH1A1HSD17B10POLBCA12
SCHEMBL2646567 0.77 HSD17B10 (0.46) KDM4EALDH1A1HSD17B10METAP2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107014934-B Quality control product of urine organic acid filter paper and preparation method thereof 广州金域医学检验中心有限公司 2020-12-08 CN disclosed
US-20090042946-A1 METHOD AND KIT FOR CONTROLLING BLEEDING MOORE II BOB M 2009-02-12 US disclosed
EP-1635689-A4 METHOD AND KIT FOR CONTROLLING BLEEDING UNIV TENNESSEE RES FOUNDATION (US) 2008-10-15 EP disclosed
US-20070037851-A1 Inhibits binding of CCR3 ligands such as eotaxins to their target cells; inhibits physiological effects of binding; therapeutic and prophylactic agents for asthma, rhinitis, dermatitis, urticaria, conjunctivitis, inflammatory bowel; tissue infiltration of eosinophils, basophils, activated T cells TEIJIN LIMITED, A JAPANESE BODY CORPORATE (JP) 2007-02-15 US disclosed
EP-1635689-A2 METHOD AND KIT FOR CONTROLLING BLEEDING University of Tennessee Research Foundation (US) 2006-03-22 EP disclosed
WO-2004093664-A2 METHOD AND KIT FOR CONTROLLING BLEEDING UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2004-11-04 WO disclosed
US-20040202735-A1 Method and kit for controlling bleeding UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2004-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070037851-A1 Inhibits binding of CCR3 ligands such as eotaxins to their target cells; inhibits physiological effects of binding; therapeutic and prophylactic agents for asthma, rhinitis, dermatitis, urticaria, conjunctivitis, inflammatory bowel; tissue infiltration of eosinophils, basophils, activated T cells CCR3, CCR1, CCR4 DRD2 971/4885KDM4E 3617/4885ALDH1A1 486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.