Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10240830 | 1.00 | MAPT (0.50) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL418073 | 1.00 | MAPT (0.50) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL418694 | 0.93 | CHRNA7 (0.48) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL416609 | 0.93 | CHRNA7 (0.48) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL10240840 | 0.93 | CHRNA7 (0.48) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL416230 | 0.89 | EGFR (0.43) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL416229 | 0.89 | EGFR (0.43) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL10242548 | 0.89 | EGFR (0.43) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL10242540 | 0.88 | MAPT (0.46) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL416432 | 0.88 | MAPT (0.46) | MAPTLMNAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106035343-A | Insecticidal triazines and pyrimidines | 韦斯塔隆公司 | 2016-10-26 | — | — | CN | claimed |
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | claimed |
| US-9321735-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2016-04-26 | — | — | US | claimed |
| US-8785630-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2014-07-22 | — | — | US | claimed |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-10-10 | — | — | US | claimed |
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2013-06-13 | — | — | US | claimed |
| EP-2595965-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2013-05-29 | — | — | EP | claimed |
| CN-103052628-A | Triazine and pyrimidine insecticides | VESTARON CORP | 2013-04-17 | — | — | CN | claimed |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2012-01-26 | — | — | US | claimed |
| WO-2012012528-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2012-01-26 | — | — | WO | claimed |
| CN-106035343-B | Triazines and pyrimidine insecticides | 韦斯塔隆公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-106035343-A | Insecticidal triazines and pyrimidines | 韦斯塔隆公司 | 2016-10-26 | — | — | CN | disclosed |
| EP-2595965-B1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | VESTARON CORP (US) | 2016-06-22 | — | — | EP | disclosed |
| CN-103052628-B | Triazine and pyrimidine insecticides | VESTARON CORP. (US) | 2016-05-18 | — | — | CN | disclosed |
| US-9321735-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2016-04-26 | — | — | US | disclosed |
| US-8389718-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389718-B2 | Insecticidal triazines and pyrimidines | Vestaron Corporation (US) | 2013-03-05 | — | — | US | disclosed |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | Vestaron Corporation (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2012012528-A1 | INSECTICIDAL TRIAZINES AND PYRIMIDINES | Vestaron Corporation (US) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150365-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | MAPT 3000/4885LMNA 4005/4885MEN1 4237/4885 |
| US-20120022066-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | MAPT 3000/4885LMNA 4005/4885MEN1 4237/4885 |
| US-20130267705-A1 | Insecticidal Triazines and Pyrimidines | TYMS, TYMP, DHX15 | MAPT 3000/4885LMNA 4005/4885MEN1 4237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.