Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4441912 | 0.93 | MMP12 (0.60) | MMP12MMP13 | |
| SCHEMBL4441906 | 0.93 | MMP12 (0.60) | MMP12MMP13 | |
| SCHEMBL4152865 | 0.90 | MMP12 (0.58) | MMP12MMP13 | |
| SCHEMBL8198910 | 0.89 | MMP12 (0.66) | MMP12MMP13 | |
| SCHEMBL4160884 | 0.87 | MMP12 (0.60) | MMP12MMP13 | |
| SCHEMBL4167772 | 0.86 | MMP12 (0.59) | MMP12MMP13 | |
| SCHEMBL4556537 | 0.86 | MMP12 (0.59) | MMP12MMP13 | |
| SCHEMBL4013413 | 0.85 | MMP12 (0.57) | MMP12MMP13 | |
| SCHEMBL4013101 | 0.85 | MMP12 (0.57) | MMP12MMP13 | |
| SCHEMBL4165859 | 0.85 | MMP12 (0.59) | MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074107-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2009-07-01 | — | — | EP | claimed |
| WO-2008057254-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH (US) | 2008-05-15 | — | — | WO | claimed |
| EP-2074107-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | Wyeth a Corporation of the State of Delaware (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008057254-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH (US) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008057254-A2 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH (US) | 2008-05-15 | — | — | WO | disclosed |