Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5663847 | 0.85 | CDC7 (0.49) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL16356488 | 0.82 | KCNH2 (0.47) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL14259391 | 0.82 | KCNH2 (0.53) | KCNH2MGLLKDM4EALDH1A1HPGD | |
| SCHEMBL16356716 | 0.78 | KCNH2 (0.52) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL6597949 | 0.78 | MIF (0.45) | KCNH2PLA2G4AKDM4EALDH1A1HPGD | |
| SCHEMBL3131128 | 0.78 | PLA2G4A (0.51) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL15712437 | 0.78 | SMN1; SMN2 (0.55) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL5737678 | 0.78 | PLA2G4A (0.55) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL4557834 | 0.78 | BIRC5 (0.62) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 | |
| SCHEMBL17067770 | 0.78 | FGFR1 (0.51) | KCNH2PLA2G4AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118850-A | Method for preparing amino phenethyl alcohol compound by reforming indole compound structure | 中国科学院兰州化学物理研究所 | 2024-12-13 | — | — | CN | disclosed |
| US-20120065225-A1 | HETEROARYL PYRROLIDINYL AND PIPERIDINYL KETONE DERIVATIVES AND USES THEREOF | IYER PRAVIN (US) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065225-A1 | HETEROARYL PYRROLIDINYL AND PIPERIDINYL KETONE DERIVATIVES AND USES THEREOF | CNKSR1, RB1, AR | KCNH2 630/4885PLA2G4A 4460/4885HDAC3 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.