SCHEMBL415618

SCHEMBL415618

NC(=O)CCOC(=O)Nc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.61
RAB9A P51151 5/20 0.61
SMN1; SMN2 Q16637 5/20 0.61
TSHR P16473 1/20 0.61
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
RECQL P46063 1/20 0.59
NPSR1 Q6W5P4 2/20 0.57
LMNA P02545 3/20 0.54
TP53 P04637 2/20 0.54
ALDH1A1 P00352 2/20 0.50
MAPK1 P28482 1/20 0.50
MAPT P10636 1/20 0.50
CHRNA7 P36544 1/20 0.49
MGLL Q99685 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910269 0.86 NPC1 (0.65) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL8231705 0.83 SMN1; SMN2 (0.55) NPC1RAB9ASMN1; SMN2RECQLLMNA
SCHEMBL13827477 0.82 NPC1 (0.65) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL10597471 0.82 RAB9A (0.77) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL2056327 0.81 SMN1; SMN2 (0.56) NPC1RAB9ASMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL320269 0.81 NPC1 (0.63) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL17346621 0.80 NPC1 (0.72) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL17263428 0.80 RAB9A (0.75) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL10817231 0.80 RAB9A (0.75) NPC1RAB9ASMN1; SMN2TSHRMEN1
SCHEMBL10596423 0.80 NPC1 (0.72) NPC1RAB9ASMN1; SMN2TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250277230-A1 PARTHENOGENESIS METHODS AND COMPOSITIONS PIONEER HI-BRED INTERNATONAL, INC. (US) 2025-09-04 US disclosed
US-20240002877-A1 PARTHENOGENESIS FACTORS AND METHODS OF USING SAME PIONEER HI-BRED INTERNATIONAL, INC. (US) 2024-01-04 US disclosed
US-9121032-B2 Selective ablation of diploid embryos E I DU PONT DE NEMOURS AND COMPANY (US) 2015-09-01 US disclosed
US-8859846-B2 Doubling of chromosomes in haploid embryos E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-10-14 US disclosed
US-20120311736-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E.I. du Pont de Nemours and Company and Pioneer Hi-Bred International 2012-12-06 US disclosed
US-8269061-B2 Selective ablation of diploid embryos E.I. du Pont de Nmeours and Company (US) 2012-09-18 US disclosed
US-20120023612-A1 SELECTIVE ABLATION OF DIPLOID EMBRYOS E. I. DU PONT DE NEMOURS AND COMPANY AND PIONEER HI-BRED INTERNATIONAL, INC. (US) 2012-01-26 US disclosed
US-20080216191-A1 Pollinating silks of maize ear, contacting haploid embryo with chromosome doubling agent (colchicine), propagate cells; generating homozygosity in plants PIONEER HI-BRED INTERNATIONAL, INC. (US) 2008-09-04 US disclosed
US-5688745-A Arylsulfonylureas and their use as herbicides and growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-18 US disclosed