Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30636783 | 1.00 | KDM4E (0.48) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL31627791 | 0.80 | KDM4E (0.43) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL3791254 | 0.78 | KDM4E (0.50) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL27658146 | 0.78 | CKS1B (0.46) | KDM4ELMNAHIF1ANPC1ADORA2A | |
| SCHEMBL29871060 | 0.78 | KDM4E (0.50) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL176039 | 0.74 | KDM4E (0.68) | KDM4ELMNAHIF1ACCR1CCR5 | |
| Dipyridyl SCHEMBL28393736 | 0.74 | KDM4E (0.78) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL230048 | 0.74 | KDM4E (0.60) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL29531176 | 0.74 | KDM4E (0.60) | KDM4ELMNAHIF1ACCR1CCR5 | |
| SCHEMBL8567845 | 0.73 | KDM4E (0.43) | KDM4ELMNAHIF1ACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181941-A1 | Pyrrolopyrimidines and Pyrrolopyridines | NOVARTIS AG (CH) | 2009-07-16 | — | — | US | claimed |
| CN-117616032-A | Rare earth complex | 东曹株式会社 | 2024-02-27 | — | — | CN | disclosed |
| CN-107129463-A | Dipyridyl derivatives of polyfunctional group substitution and preparation method thereof | 福州大学 | 2017-09-05 | — | — | CN | disclosed |
| CN-105001152-A | 11 beta-HSD1 inhibitor of dimethylamino bipyridine tertiary alcohol structure and application thereof | FOSHAN SAIWEISI MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2015-10-28 | — | — | CN | disclosed |
| CN-105001152-A | 11 beta-HSD1 inhibitor of dimethylamino bipyridine tertiary alcohol structure and application thereof | FOSHAN SAIWEISI MEDICINE SCIENCE & TECHNOLOGY CO LTD | 2015-10-28 | — | — | CN | disclosed |
| CN-1322254-A | Small volume in vitro analytical sensor containing diffusible or non-leachable redox mediator | THERASENSE INC (US) | 2001-11-14 | — | — | CN | disclosed |
| EP-0885183-A1 | PROCESS FOR PRODUCING ALDEHYDES BY HYDROFORMYLATION OF OLEFINS | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997028113-A1 | PROCESS FOR PRODUCING ALDEHYDES BY HYDROFORMYLATION OF OLEFINS | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181941-A1 | Pyrrolopyrimidines and Pyrrolopyridines | ALK, ACVR1, PTPN4 | KDM4E 448/4885LMNA 2708/4885HIF1A 2582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.