SCHEMBL4156622

SCHEMBL4156622

CC1(C)CCCCC1C1CCCC2C3CCCCC3CC21

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.37
GRIN1 Q05586 1/20 0.33
GRIN2B Q13224 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4155063 0.82 HSD17B10 (0.37) HSD17B10
SCHEMBL4160302 0.82 HSD17B10 (0.33) HSD17B10GRIN1GRIN2B
SCHEMBL4156823 0.79 HSD17B10 (0.33) HSD17B10GRIN1GRIN2B
SCHEMBL3000274 0.79 GRIN1 (0.42) HSD17B10GRIN1GRIN2B
SCHEMBL4161808 0.76
SCHEMBL4164197 0.72 GAA (0.31)
SCHEMBL4160067 0.72
SCHEMBL10760869 0.71 HSD17B10 (0.34) HSD17B10
SCHEMBL30487174 0.71 MAPT (0.39) HSD17B10
SCHEMBL2994151 0.70 HSD17B10 (0.36) HSD17B10GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2009304-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-10-01 EP disclosed
EP-2003353-B1 TORQUE LIMITER JTEKT CORP (JP) 2014-06-04 EP disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed