Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6756605 | 0.85 | CDK5 (0.35) | GRIN1GRIN2BHSD17B10CDK5CDK5R1 | |
| SCHEMBL2994151 | 0.81 | HSD17B10 (0.36) | GRIN1GRIN2BHSD17B10CDK5CDK5R1 | |
| SCHEMBL4156622 | 0.79 | HSD17B10 (0.37) | GRIN1GRIN2BHSD17B10 | |
| SCHEMBL10760869 | 0.78 | HSD17B10 (0.34) | HSD17B10 | |
| SCHEMBL7353210 | 0.75 | GRIN1 (0.55) | GRIN1GRIN2BCDK5CDK5R1NR1I3 | |
| SCHEMBL374356 | 0.75 | GRIN1 (0.55) | GRIN1GRIN2BCDK5CDK5R1NR1I3 | |
| Charcoal, Activated SCHEMBL4630579 | 0.74 | GRIN1 (0.53) | GRIN1GRIN2BCDK5CDK5R1NR1I3 | |
| Ethyne SCHEMBL7015681 | 0.72 | GRIN1 (0.52) | GRIN1GRIN2BCDK5CDK5R1NR1I3 | |
| SCHEMBL4160302 | 0.71 | HSD17B10 (0.33) | GRIN1GRIN2BHSD17B10 | |
| SCHEMBL2994786 | 0.71 | LIPA (0.35) | GRIN1GRIN2BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2009304-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-10-01 | — | — | EP | disclosed |
| EP-2003353-B1 | TORQUE LIMITER | JTEKT CORP (JP) | 2014-06-04 | — | — | EP | disclosed |
| US-8230986-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-31 | — | — | US | disclosed |
| US-8220609-B2 | Torque limiter | JTEKT CORPORATION (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20100184519-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090173591-A1 | TORQUE LIMITER | JTEKT CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2009304-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |
| EP-2003353-A1 | TORQUE LIMITER | JTEKT Corporation (JP) | 2008-12-17 | — | — | EP | disclosed |