SCHEMBL4156766

SCHEMBL4156766

CCCCCN(CCCCC)C(C)=O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA9 Q16790 3/20 0.50
CA2 P00918 1/20 0.48
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP3 P08254 1/20 0.46
MMP8 P22894 1/20 0.46
MGLL Q99685 1/20 0.43
ZDHHC20 Q5W0Z9 2/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
CES2 O00748 4/20 0.42
CES1 P23141 4/20 0.42
DNM1 Q05193 3/20 0.42
AKR1B1 P15121 1/20 0.40
ALDH1A1 P00352 1/20 0.39
ALDH2 P05091 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4149053 0.97 CA12 (0.52) CA12CA1CA9CA2MMP1
SCHEMBL4139404 0.97 CA12 (0.52) CA12CA1CA9CA2MMP1
SCHEMBL4163491 0.97 CA12 (0.52) CA12CA1CA9CA2MMP1
SCHEMBL8431297 0.97 CA12 (0.52) CA12CA1CA9CA2MMP1
SCHEMBL2482724 0.97 CA12 (0.52) CA12CA1CA9CA2MMP1
SCHEMBL11343070 0.97 CA12 (0.52) CA12CA1CA9CA2MMP1
SCHEMBL1742678 0.97 CA12 (0.52) CA12CA1CA9CA2MMP1
SCHEMBL2481657 0.97 CA12 (0.52) CA12CA1CA9CA2MMP1
SCHEMBL4155109 0.97 CA12 (0.52) CA12CA1CA9CA2MMP1
SCHEMBL6940598 0.97 CA12 (0.52) CA12CA1CA9CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026839-A Purification method and application of high-purity succinic acid 安徽丰原发酵技术工程研究有限公司 2024-05-14 CN claimed
CN-116203096-A All-solid-state sodium ion selective electrode, preparation method thereof and application thereof in bioelectrolyte detection 广州钰芯传感科技有限公司 2023-06-02 CN claimed
CN-115253872-A Control system for controlling rotating speed of high-speed stirrer through feedback of volatile organic compound recovery parameters 浙江省建筑材料科学研究所有限公司 2022-11-01 CN claimed
CN-114380683-A Method for extracting lactic acid from fermentation liquor containing calcium lactate 安徽丰原发酵技术工程研究有限公司 2022-04-22 CN claimed
CN-114276235-A Method for extracting citric acid from fermentation liquor containing citric acid 安徽丰原发酵技术工程研究有限公司 2022-04-05 CN claimed
EP-3294735-B1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMA (US) 2021-10-27 EP claimed
US-20200207765-A1 METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMACEUTICALS INCORPORATED 2020-07-02 US claimed
EP-3068776-B1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMA (US) 2019-05-29 EP claimed
US-10273233-B2 Inhibitors of influenza viruses replication VERTEX PHARMACEUTICALS INCORPORATED (US) 2019-04-30 US claimed
US-20180282330-A1 METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMACEUTICALS INCORPORATED 2018-10-04 US claimed
US-20160251354-A1 METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMACEUTICALS INCORPORATED 2016-09-01 US claimed
WO-2015073481-A1 METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMACEUTICALS INCORPORATED (US) 2015-05-21 WO claimed
WO-2015073476-A1 INHIBITORS OF INFLUENZA VIRUSES REPLICATION VERTEX PHARMACEUTICALS INCORPORATED (US) 2015-05-21 WO claimed
US-6787149-B1 Topical application of opioid analgesic drugs such as morphine EL KHOURY AND STEIN LTD. 2004-09-07 US claimed
EP-1082006-A1 CRYOPRESERVATION OF HUMAN RED BLOOD CELLS LIFECELL CORPORATION (US) 2001-03-14 EP claimed
US-6143278-A TOPICAL ADMINISTRATION OF OPIOID ANALGESIC AGENT IN ADMIXTURE WITH SKIN OR MUCOSAL SPECIFIC PENETRATION ENHANCER TO PRODUCE LOCALIZED ANALGESIC EFFECT IN SKIN OR MUCOSAL TISSUE WITHOUT TRANSDERMAL MIGRATION OF OPIOD AGENT ELKHOURY GEORGE F (US) 2000-11-07 US claimed
WO-1999060849-A1 CRYOPRESERVATION OF HUMAN RED BLOOD CELLS LIFECELL CORPORATION (US) 1999-12-02 WO claimed
EP-0153400-A1 BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF SUCH COMPOUNDS AND COMPOSITIONS SCHERING CORPORATION (US) 1985-09-04 EP claimed
EP-0135767-A1 Benzazepine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions SCHERING CORPORATION (US) 1985-04-03 EP claimed
WO-1985000808-A1 BENZAZEPINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF SUCH COMPOUNDS AND COMPOSITIONS SCHERING CORP. (US) 1985-02-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180282330-A1 METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION ZC3HAV1, ZC3HAV1L, POLR2H CA12 803/4885CA1 655/4885CA9 98/4885
US-20160251354-A1 METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION ZC3HAV1, ZC3HAV1L, POLR2H CA12 803/4885CA1 655/4885CA9 98/4885
US-10273233-B2 Inhibitors of influenza viruses replication ZC3HAV1, ZC3HAV1L, RCC1 CA12 2703/4885CA1 1841/4885CA9 1050/4885
US-20200207765-A1 METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION ZC3HAV1, ZC3HAV1L, POLR2H CA12 803/4885CA1 655/4885CA9 98/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.