SCHEMBL4156967

SCHEMBL4156967

COC(=O)[C@@H](Cc1ccc(O)cc1)Nc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.61
PPARA Q07869 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1749468 1.00 PPARG (0.61) PPARGPPARA
SCHEMBL1719719 1.00 PPARG (0.61) PPARGPPARA
SCHEMBL7920805 0.94 PPARG (0.55) PPARGPPARA
SCHEMBL1719565 0.92 PPARG (0.53) PPARGPPARA
SCHEMBL1720449 0.92 PPARG (0.61) PPARGPPARA
SCHEMBL7921154 0.91 PPARG (0.62) PPARGPPARA
SCHEMBL4159916 0.91 PPARG (0.61) PPARGPPARA
SCHEMBL1720475 0.89 PPARG (0.50) PPARG
SCHEMBL1720416 0.88 PPARG (0.53) PPARG
SCHEMBL2217249 0.88 PPARG (0.76) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090088438-A1 NEW TYROSINE DERIVATIVES AS PPARy MODULATORS LABORATORIOS SALVAT, S.A. (ES) 2009-04-02 US disclosed
US-7423172-B2 Tyrosine derivatives as PPAR-γ-modulators LABORATORIOS SALVAT, S.A. (ES) 2008-09-09 US disclosed
EP-1778624-B1 TYROSINE DERIVATIVES AS PPAR-GAMMA-MODULATORS SALVAT LAB SA (ES) 2008-08-20 EP disclosed
US-20070276043-A1 Tyrosine Derivatives As Ppar-Gamma-Modulators LABORATORIES SALVAT, S.A. (ES) 2007-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088438-A1 NEW TYROSINE DERIVATIVES AS PPARy MODULATORS PPARG, PPARD, TYRO3 PPARG 1/4885PPARA 4/4885
US-20070276043-A1 Tyrosine Derivatives As Ppar-Gamma-Modulators PPARG, PPARD, PPARA PPARG 1/4885PPARA 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.