Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290549 | 1.00 | PPARG (0.76) | PPARGPPARA | |
| SCHEMBL28214088 | 0.93 | PPARG (0.66) | PPARGPPARA | |
| SCHEMBL9751930 | 0.92 | PPARG (0.79) | PPARGPPARA | |
| SCHEMBL4156967 | 0.88 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL1719719 | 0.88 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL1749468 | 0.88 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL27413268 | 0.87 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL8335329 | 0.86 | PPARG (0.72) | PPARGPPARA | |
| SCHEMBL11878375 | 0.86 | PPARG (0.61) | PPARG | |
| SCHEMBL2785014 | 0.86 | PPARG (0.88) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103211819-A | Administration of dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL | 2013-07-24 | — | — | CN | disclosed |
| CN-102834393-A | Apoptosis signal-regulating kinase 1 inhibitors | TAKEDA PHARMACEUTICAL CORP | 2012-12-19 | — | — | CN | disclosed |
| CN-101309689-B | Dipeptidyl peptidase inhibitors for the treatment of diabetes | TAKAEDA CHEMICAL IND LTD | 2012-10-10 | — | — | CN | disclosed |
| CN-101267838-B | Use of DPP-IV inhibitors to reduce hypoglycemic events | NOVARTIS AG | 2012-09-05 | — | — | CN | disclosed |
| CN-101374523-B | Dipeptidyl peptidase inhibitors for the treatment of diabetes | TAKEDA PHARMACEUTICAL | 2012-04-11 | — | — | CN | disclosed |
| CN-102327614-A | Combinations comprising dipeptidylpeptidase - iv inhibitor | NOVARTIS AG | 2012-01-25 | — | — | CN | disclosed |
| CN-101035522-B | Combination of DPP-IV inhibitor, PPAR antidiabetic and metformin | NOVARTIS AG (CH) | 2011-12-07 | — | — | CN | disclosed |
| CN-102210865-A | Concomitant pharmaceutical agents and use thereof | MITSUBISHI TANABE PHARMA CORP | 2011-10-12 | — | — | CN | disclosed |
| CN-102188705-A | Medicament composition containing bis cyclooctane derivatives | LIYAN WANG | 2011-09-21 | — | — | CN | disclosed |
| CN-102166215-A | Pharmaceutical composition containing piperazine derivatives | LIYAN WANG | 2011-08-31 | — | — | CN | disclosed |
| WO-2002094877-A2 | NEW NUCLEAR RECEPTOR COFACTORS AND RELATED MODULATORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2002-11-28 | — | — | WO | disclosed |
| CN-1093124-C | Substituted 4-hydroxy-phenylalcanoic acid derivatives with activity to ppar-'gamma' | GLAXO GROUP LTD (GB) | 2002-10-23 | — | — | CN | disclosed |
| WO-2002076435-A2 | LIPID PROFILE MODULATION WITH STEROIDS | THE UNIVERSITY OF EDINBURGH (GB) | 2002-10-03 | — | — | WO | disclosed |
| US-6294580-B1 | FOR THERAPY AND PROPHYLAXIS OF TYPE II OR NON-INSULIN DEPENDENT DIABETES MELLITUS, HYPERGLYCAEMIA, DYSLIPIDEMIA, TYPE II DIABETES, TYPE I DIABETES, HYPERTRIGLYCERIDEMIA, SYNDROME X, INSULIN RESISTANCE, HEART FAILURE | GLAXO WELLCOME INC. | 2001-09-25 | — | — | US | disclosed |
| US-6291496-B1 | E.G., WITH OVEREXPRESSSION OF HER-2/NEU OR OVEREXPRESSION OF EPIDERMAL GROWTH FACTOR RECEPTOR, ARE TREATED WITH STRONGLY BINDING PPAR GAMMA LIGANDS. | CORNELL RESEARCH FOUNDATION, INC. | 2001-09-18 | — | — | US | disclosed |
| EP-0888317-B1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LTD (GB) | 2001-09-12 | — | — | EP | disclosed |
| WO-2001047555-A1 | TREATING CANCERS ASSOCIATED WITH OVEREXPRESSION OF CLASS I FAMILY OF RECEPTOR TYROSINE KINASES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2001-07-05 | — | — | WO | disclosed |
| CN-1218460-A | Substituted 4-hydroxy-phenylalcanoic acid derivatives with activity to ppar-'gamma' | GLAXO GROUP LTD (GB) | 1999-06-02 | — | — | CN | disclosed |
| EP-0888317-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997031907-A1 | SUBSTITUTED 4-HYDROXY-PHENYLALCANOIC ACID DERIVATIVES WITH AGONIST ACTIVITY TO PPAR-GAMMA | GLAXO GROUP LIMITED (GB) | 1997-09-04 | — | — | WO | disclosed |