SCHEMBL4157038

SCHEMBL4157038

C=CCOc1ccc(C=CC(=O)c2c(O)cc(OCOC)cc2OCOC)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 4/20 0.69
SLC5A2 P31639 4/20 0.69
ABCG2 Q9UNQ0 3/20 0.56
FLT3 P36888 1/20 0.54
NFKB1 P19838 1/20 0.53
DPP4 P27487 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
MKNK2 Q9HBH9 1/20 0.49
MAPT P10636 4/20 0.49
CYP3A4 P08684 3/20 0.49
KMT2A Q03164 3/20 0.49
TP53 P04637 2/20 0.49
ATM Q13315 1/20 0.49
HSD17B10 Q99714 1/20 0.49
BCHE P06276 2/20 0.48
ACHE P22303 2/20 0.48
TDP1 Q9NUW8 3/20 0.48
KDM4E B2RXH2 2/20 0.48
MEN1 O00255 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31233390 1.00 SLC5A1 (0.69) SLC5A1SLC5A2ABCG2FLT3NFKB1
SCHEMBL13741092 1.00 SLC5A1 (0.69) SLC5A1SLC5A2ABCG2FLT3NFKB1
SCHEMBL9578204 0.92 ABCG2 (0.64) SLC5A1SLC5A2ABCG2NFKB1DPP4
SCHEMBL9578210 0.92 ABCG2 (0.64) SLC5A1SLC5A2ABCG2NFKB1DPP4
SCHEMBL25206841 0.90 SLC5A1 (0.80) SLC5A1SLC5A2ABCG2FLT3NFKB1
SCHEMBL15681495 0.89 ABCG2 (0.60) SLC5A1SLC5A2ABCG2NFKB1DPP4
SCHEMBL25195561 0.88 ABCG2 (0.72) SLC5A1SLC5A2ABCG2NFKB1DPP4
SCHEMBL31233305 0.88 ABCG2 (0.72) SLC5A1SLC5A2ABCG2NFKB1DPP4
SCHEMBL25265079 0.88 ABCG2 (0.72) SLC5A1SLC5A2ABCG2NFKB1DPP4
SCHEMBL10844791 0.86 ABCG2 (0.76) SLC5A1SLC5A2ABCG2FLT3NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
US-8710097-B2 Flavonoid dimers and methods of making and using such THE HONG KONG POLYTECHNIC UNIVERSITY (CN) 2014-04-29 US disclosed
US-20090197943-A1 Flavonoid Dimers and Methods of Making and Using Such THE HONG KONG POLYTECHNIC UNIVERSITY (CN) 2009-08-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B SLC5A1 3752/4885SLC5A2 4208/4885ABCG2 1606/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 SLC5A1 4485/4885SLC5A2 4756/4885ABCG2 3622/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 SLC5A1 4485/4885SLC5A2 4756/4885ABCG2 3622/4885
US-20090197943-A1 Flavonoid Dimers and Methods of Making and Using Such ABCB1, ABCC1, SLC47A2 SLC5A1 1379/4885SLC5A2 673/4885ABCG2 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.